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Aquaporin 5 抗体 (C-Term)

Cited in 2+ publications. This 兔 多克隆 anti-Aquaporin 5 antibody specifically detects Aquaporin 5 in WB 和 IHC. The antibody is reactive with 小鼠 和 大鼠 samples.
产品编号 ABIN3043712
发货至: 中国
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Quick Overview for Aquaporin 5 抗体 (C-Term) (ABIN3043712)

抗原

See all Aquaporin 5 (AQP5) 抗体
Aquaporin 5 (AQP5)

适用

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小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Aquaporin 5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 246-265, C-Term

    原理

    Anti-Aquaporin 5/AQP5 Antibody

    序列

    EEDWEDHREE RKKTIELTAH

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Aquaporin 5/AQP5 Antibody (ABIN3043712). Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse AQP5, identical to the related rat sequence.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Mouse
    Western blot, 0.1-0.5 μg/mL, Rat, Mouse

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Guo, Kazadaeva, Ortega, Manjunath, Desai: "Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung." in: Developmental biology, Vol. 430, Issue 1, pp. 214-223, (2017) (PubMed).

    Chen, Zhou, Yan, Ma, Zheng: "Hyperosmotic stress induces cisplatin sensitivity in ovarian cancer cells by stimulating aquaporin-5 expression." in: Experimental and therapeutic medicine, Vol. 10, Issue 6, pp. 2055-2062, (2015) (PubMed).

  • 抗原

    Aquaporin 5 (AQP5)

    别名

    AQP5

    背景

    Synonyms: Aquaporin-5;AQP-5;Aqp5;

    Background: Aquaporin 5, also known as AQP5, is a water channel protein. The aquaporins (AQPs) are a family of more than 10 homologous water transporting proteins expressed in many mammalian epithelia and endothelia. At least five AQPs are expressed in the eye: AQP0 (MIP) in lens fiber, AQP1 in cornea endothelium, ciliary and lens epithelia and trabecular meshwork, AQP3 in conjunctiva, AQP4 in ciliary epithelium and retinal Müller cells, and AQP5 in corneal and lacrimal gland epithelia. Among the seven human aquaporins cloned to date (AQPs 0-6), genes encoding the four most closely related aquaporins (AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions.

    分子量

    62 kDa
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