Aquaporin 5 抗体 (C-Term)
(2 references)Quick Overview for Aquaporin 5 抗体 (C-Term) (ABIN3043712)
抗原
See all Aquaporin 5 (AQP5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 246-265, C-Term
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原理
- Anti-Aquaporin 5/AQP5 Antibody Picoband®
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序列
- EEDWEDHREE RKKTIELTAH
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Aquaporin 5/AQP5 Antibody (ABIN3043712). Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of mouse AQP5, identical to the related rat sequence.
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亚型
- IgG
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anti-Aquaporin 5 (AQP5) (AA 201-265) antibody
AQP5 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 5 (AQP5) (C-Term) antibodyAQP5 适用: 人, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 5 (AQP5) (AA 150-250) antibodyAQP5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 5 (AQP5) (AA 201-265) antibody (Biotin)AQP5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
anti-Aquaporin 5 (AQP5) (AA 227-256), (C-Term) antibodyAQP5 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB31077 unconjugated
anti-Aquaporin 5 (AQP5) (C-Term) antibodyAQP5 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 5 (AQP5) antibodyAQP5 适用: 人 IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 5 (AQP5) (C-Term) antibodyAQP5 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 5 (AQP5) (AA 227-256) antibodyAQP5 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 5 (AQP5) (AA 251-265), (Intracellular) antibodyAQP5 适用: 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Rat, Mouse
1. Verkman AS (2003). "Role of aquaporin water channels in eye function.". Exp. Eye Res. 76 (2): 137-43. 2. Ma T, Yang B, Umenishi F, Verkman AS (1997). "Closely spaced tandem arrangement of AQP2, AQP5, and AQP6 genes in a 27-kilobase segment at chromosome locus 12q13.". Genomics 43 (3): 387-9. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung." in: Developmental biology, Vol. 430, Issue 1, pp. 214-223, (2017) (PubMed).
: "Hyperosmotic stress induces cisplatin sensitivity in ovarian cancer cells by stimulating aquaporin-5 expression." in: Experimental and therapeutic medicine, Vol. 10, Issue 6, pp. 2055-2062, (2015) (PubMed).
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: "Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung." in: Developmental biology, Vol. 430, Issue 1, pp. 214-223, (2017) (PubMed).
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- Aquaporin 5 (AQP5)
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别名
- AQP5
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背景
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Synonyms: Aquaporin-5;AQP-5;Aqp5;
Background: Aquaporin 5, also known as AQP5, is a water channel protein. The aquaporins (AQPs) are a family of more than 10 homologous water transporting proteins expressed in many mammalian epithelia and endothelia. At least five AQPs are expressed in the eye: AQP0 (MIP) in lens fiber, AQP1 in cornea endothelium, ciliary and lens epithelia and trabecular meshwork, AQP3 in conjunctiva, AQP4 in ciliary epithelium and retinal Müller cells, and AQP5 in corneal and lacrimal gland epithelia. Among the seven human aquaporins cloned to date (AQPs 0-6), genes encoding the four most closely related aquaporins (AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions.
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分子量
- 62 kDa
抗原
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