Annexin a1 抗体 (N-Term)
(3 references)Quick Overview for Annexin a1 抗体 (N-Term) (ABIN3043680)
抗原
See all Annexin a1 (ANXA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3-24, N-Term
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原理
- Anti-Annexin A1/ANXA1 Antibody Picoband®
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序列
- MVSEFLKQAW FIENEEQEYV QT
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Annexin A1/ANXA1 Antibody (ABIN3043680). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Annexin A1.
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亚型
- IgG
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anti-Annexin A1 (ANXA1) (AA 6-346) antibody
ANXA1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (AA 1-346) antibodyANXA1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal ANXA1-3566 unconjugated
anti-Annexin A1 (ANXA1) (AA 144-248) antibodyANXA1 适用: 人, 小鼠, 猴 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 WB, IP, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (C-Term) antibodyVerified ANXA1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (AA 1-346) antibodyANXA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Annexin A1 (ANXA1) (AA 1-346) antibodyANXA1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 IHC, FACS, StM 宿主: 小鼠 Monoclonal ANXA1-1671 unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Monkey
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Wallner, B. P., Mattaliano, R. J., Hession, C., Cate, R. L., Tizard, R., Sinclair, L. K., Foeller, C., Chow, E. P., Browning, J. L., Ramachandran, K. L., Pepinsky, R. B. : Cloning and expression of human lipocortin, a phospholipase A2 inhibitor with potential anti-inflammatory activity. Nature 320: 77-81, 1986. . 2. Kovacic RT, Tizard R, Cate RL, Frey AZ, Wallner BP. Correlation of gene and protein structure of rat and human lipocortin I. Biochemistry. 1991 Sep 17,30(37):9015-21. 3. Walther, A., Riehemann, K., Gerke, V. A novel ligand of the formyl peptide receptor: annexin I regulates neutrophil extravasation by interacting with the FPR. Molec. Cell 5: 831-840, 2000. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "The prognostic value and clinicopathological features of sarcomatoid differentiation in patients with renal cell carcinoma: a systematic review and meta-analysis." in: Cancer management and research, Vol. 10, pp. 1687-1703, (2018) (PubMed).
: "Ancient and modern anticonvulsants act synergistically in a KCNQ potassium channel binding pocket." in: Nature communications, Vol. 9, Issue 1, pp. 3845, (2018) (PubMed).
: "Influence of type 2 diabetes on local production of inflammatory molecules in adults with and without chronic periodontitis: a cross-sectional study." in: BMC oral health, Vol. 15, pp. 86, (2015) (PubMed).
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: "The prognostic value and clinicopathological features of sarcomatoid differentiation in patients with renal cell carcinoma: a systematic review and meta-analysis." in: Cancer management and research, Vol. 10, pp. 1687-1703, (2018) (PubMed).
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- Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
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别名
- ANXA1
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背景
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Synonyms: Annexin A1,Annexin I,Annexin-1,Calpactin II,Calpactin-2,Chromobindin-9,Lipocortin I,Phospholipase A2 inhibitory protein,p35,ANXA1,ANX1, LPC1,
Tissue Specificity: Widely expressed, with highest expression in brain. .
Background: Annexin I, also known as lipocortin I (Lipo1), belongs to the family of annexins. These proteins are though to control the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes. In two lipocortins (I and II) a short amino-terminal sequence distinct from the core structure has potential regulatory functions which are dependent on its phosphorylation state. The gene in the mouse encodes a protein of 346 amino acid residues. Mouse Lipo1 gene spans about 17 kb and is divided into 13 exons. Annexin I gene, mapped to 9q11-q22, is located on mouse chromosome 19. Annexin I acts through the formyl peptide receptor on human neutrophils. Peptides derived from the unique N-terminal domain of annexin I serve as FPR ligands and trigger different signaling pathways in a dose-dependent manner.
Sequence Similarities: Belongs to the annexin family.
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分子量
- 39 kDa
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UniProt
- P04083
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途径
- Hormone Transport
抗原
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