MAFA 抗体 (Middle Region)
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- 抗原 See all MAFA 抗体
- MAFA (Transcription Factor MafA (MAFA))
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抗原表位
- AA 136-167, Middle Region
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAFA antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Transcription factor MafA(MAFA) detection. Tested with WB in Human,Rat.
- 序列
- EDAVEALIGS GHHGAHHGAH HPAAAAAYEA FR
- 交叉反应 (详细)
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Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Transcription factor MafA(MAFA) detection. Tested with WB in Human,Rat.
Gene Name: v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
Protein Name: Transcription factor MafA - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human MAFA(136-167aa EDAVEALIGSGHHGAHHGAHHPAAAAAYEAFR), identical to the related mouse sequence.
- 亚型
- IgG
- Top Product
- Discover our top product MAFA Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, The detection limit for MAFA is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- MAFA (Transcription Factor MafA (MAFA))
- 别名
- MAFA (MAFA 产品)
- 背景
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MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene. MAFA plays a key role in coordinating and controlling the level of insulin gene expression in islet beta cells. It is located in 8q24.3. The intracellular domain of MAFA contains a single immunoreceptor tyrosine-based inhibitory motif (ITIM), which classifies MAFA as a member of an inhibitory receptor superfamily. The inhibitory capacity of MAFA is best defined in mast cells, where MAFA keeps in check the antigen-induced (i.e. Fc epsilon RI-induced) secretion ofinflammatory mediators.
Synonyms: HMafA antibody|Mafa antibody|MAFA_HUMAN antibody|Pancreatic beta cell specific transcriptional activator antibody|Pancreatic beta-cell-specific transcriptional activator antibody|RIPE3b1 antibody|Transcription factor MafA antibody|Transcription factor RIPE3b1 antibody|v maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) antibody|v maf musculoaponeurotic fibrosarcoma oncogene homolog A antibody|V-maf musculoaponeurotic fibrosarcoma oncogene homolog A antibody - 基因ID
- 389692
- 途径
- Hormone Transport
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