电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

MAFA 抗体 (Middle Region)

This 兔 多克隆 anti-MAFA antibody specifically detects MAFA in WB. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN3043609
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MAFA 抗体 (Middle Region) (ABIN3043609)

抗原

See all MAFA 抗体
MAFA (Transcription Factor MafA (MAFA))

适用

  • 48
  • 36
  • 21
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠

宿主

  • 49
  • 3

克隆类型

  • 49
  • 3
多克隆

标记

  • 29
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MAFA antibody is un-conjugated

应用范围

  • 44
  • 16
  • 12
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 136-167, Middle Region

    原理

    Anti-Transcription factor MafA MAFA Antibody

    序列

    EDAVEALIGS GHHGAHHGAH HPAAAAAYEA FR

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Transcription factor MafA MAFA Antibody (ABIN3043609). Tested in WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human MAFA, identical to the related mouse sequence.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    MAFA (Transcription Factor MafA (MAFA))

    别名

    MAFA

    背景

    Synonyms: Transcription factor MafA,Pancreatic beta-cell-specific transcriptional activator,Transcription factor RIPE3b1,V-maf musculoaponeurotic fibrosarcoma oncogene homolog A,MAFA,

    Background: MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene. MAFA plays a key role in coordinating and controlling the level of insulin gene expression in islet beta cells. It is located in 8q24.3. The intracellular domain of MAFA contains a single immunoreceptor tyrosine-based inhibitory motif (ITIM), which classifies MAFA as a member of an inhibitory receptor superfamily. The inhibitory capacity of MAFA is best defined in mast cells, where MAFA keeps in check the antigen-induced (i.e. Fc epsilon RI-induced) secretion ofinflammatory mediators.

    Sequence Similarities: Belongs to the bZIP family. Maf subfamily.

    分子量

    37 kDa

    基因ID

    389692

    途径

    Hormone Transport
You are here: