PFN1 抗体 (C-Term)
Quick Overview for PFN1 抗体 (C-Term) (ABIN3043603)
抗原
See all PFN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 116-140, C-Term
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原理
- Anti-Profilin 1/PFN1 Antibody Picoband®
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序列
- KEGVHGGLIN KKCYEMASHL RRSQY
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Profilin 1/PFN1 Antibody Picoband® (ABIN3043603). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Profilin 1, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Profilin 1 (PFN1) (N-Term) antibody
PFN1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Profilin 1 (PFN1) (C-Term) antibodyPFN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Profilin 1 (PFN1) (AA 108-140) antibodyPFN1 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal RB55919 unconjugated
anti-Profilin 1 (PFN1) (AA 1-140) antibodyPFN1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Profilin 1 (PFN1) antibodyPFN1 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Profilin 1 (PFN1) (AA 87-120), (C-Term) antibodyPFN1 适用: 人 WB 宿主: 兔 Polyclonal RB49649 unconjugated
anti-Profilin 1 (PFN1) (AA 1-139) antibodyPFN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Profilin 1 (PFN1) (AA 1-140) antibodyPFN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Profilin 1 (PFN1) antibodyPFN1 适用: 人, 大鼠, 猴, 犬 WB, IHC, FACS, IF 宿主: 小鼠 Monoclonal 2D2 unconjugated
anti-Profilin 1 (PFN1) antibodyPFN1 适用: 人, 大鼠, 猴, 犬 WB, IHC, FACS, IF 宿主: 小鼠 Monoclonal 1D5 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. "Entrez Gene: PFN1 profilin 1" 2. Kwiatkowski, D. J., Aklog, L., Ledbetter, D. H., Morton, C. C. Identification of the functional profilin gene, its localization to chromosome subband 17p13.3, and demonstration of its deletion in some patients with Miller-Dieker syndrome. Am. J. Hum. Genet. 46: 559-567, 1990. 3. Mockrin, S. C., Korn, E. D. Acanthamoeba profilin interacts with G-actin to increase the rate of exchange of actin-bound adenosine 5-prime-triphosphate. Biochemistry 19: 5359-5362, 1980. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PFN1 (Profilin 1 (PFN1))
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别名
- PFN1
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背景
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Synonyms: Profilin-1,Epididymis tissue protein Li 184a,Profilin I,PFN1,
Tissue Specificity: Expressed in epididymis (at protein level). .
Background: Profilin-1 is a protein that in humans is encoded by the PFN1 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. PFN1 is mapped to 17p13.2. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. This gene is a 140-amino acid protein and major growth regulator of filamentous (F)-actin through its binding of monomeric (G)-actin. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome.
Sequence Similarities: Contains 1 PAC (PAS-associated C-terminal) domain.
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分子量
- 15 kDa
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基因ID
- 5216
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UniProt
- P07737
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途径
- Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location
抗原
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