OTX2 抗体 (C-Term)
Quick Overview for OTX2 抗体 (C-Term) (ABIN3043586)
抗原
See all OTX2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 258-289, C-Term
-
原理
- Anti-Otx2 Antibody Picoband®
-
序列
- DYKDQTASWK LNFNADCLDY KDQTSSWKFQ VL
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-Otx2 Antibody Picoband® (ABIN3043586). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Otx2, identical to the related mouse sequence.
-
亚型
- IgG
-
-
anti-Orthodenticle Homeobox 2 (OTX2) antibody
OTX2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1H12C4B5 unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) (N-Term) antibodyOTX2 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, 绵羊, 兔, 马, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) antibodyOTX2 适用: 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) (AA 1-297) antibodyOTX2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) (AA 86-135) antibodyOTX2 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, 绵羊, 兔, 马, Cow, 豚鼠, Bat, Hamster, Pig, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) (AA 140-280) antibodyOTX2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) antibodyOTX2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) (AA 261-289), (C-Term) antibodyOTX2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB17482 unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) (AA 261-289) antibodyOTX2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) (C-Term) antibodyOTX2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human
1. Bunt J, et al. OTX2 sustains a bivalent-like state of OTX2-bound promoters in medulloblastoma by maintaining their H3K27me3 levels. Acta Neuropathol, 2013 Mar. 2. Gat-Yablonski G. Brain development is a multi-level regulated process--the case of the OTX2 gene. Pediatr Endocrinol Rev, 2011 Sep. 3. Liu Z, et al. Specific expression pattern of a novel Otx2 splicing variant during neural differentiation. Gene, 2013 Jul 1. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- OTX2 (Orthodenticle Homeobox 2 (OTX2))
-
别名
- OTX2
-
背景
-
Synonyms: Homeobox protein OTX2,Orthodenticle homolog 2,OTX2,
Tissue Specificity: Expressed in brain.
Background: OTX2 is also known as CPHD6 or MCOPS5. This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.
Sequence Similarities: Belongs to the paired homeobox family. Bicoid subfamily.
-
分子量
- 32 kDa
-
基因ID
- 5015
-
UniProt
- P32243
-
途径
- Dopaminergic Neurogenesis
抗原
-
