NK2 Homeobox 5 抗体 (Middle Region)
Quick Overview for NK2 Homeobox 5 抗体 (Middle Region) (ABIN3043568)
抗原
See all NK2 Homeobox 5 (NKX2-5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 103-132, Middle Region
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原理
- Anti-Nkx2.5/NKX2-5 Antibody Picoband®
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序列
- AKDPRAEKKE LCALQKAVEL EKTEADNAER
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Nkx2.5/NKX2-5 Antibody Picoband® (ABIN3043568). Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human Nkx2.5, different from the related mouse and rat sequences by five amino acids.
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亚型
- IgG
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anti-NK2 Homeobox 5 (NKX2-5) (Internal Region) antibody
Verified NKX2-5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 1-324) antibodyNKX2-5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E4-G5 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 98-133) antibodyNKX2-5 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB52360 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 192-225) antibodyNKX2-5 适用: 小鼠, 大鼠, Hamster WB 宿主: 兔 Polyclonal RB51144 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) antibodyNKX2-5 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 1-130) antibodyNKX2-5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A7 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 1-130) antibodyNKX2-5 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4B11 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 1-130) antibodyNKX2-5 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 3C1 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 300-324) antibodyNKX2-5 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NK2 Homeobox 5 (NKX2-5) antibodyNKX2-5 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2E1 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse
1. Hiroi, Y., Kudoh, S., Monzen, K., Ikeda, Y., Yazaki, Y., Nagai, R., Komuro, I. Tbx5 associates withNkx2-5 and synergistically promotes cardiomyocyte differentiation. Nature Genet. 28: 276-280, 2001. 2. Shiojima, I., Komuro, I., Inazawa, J., Nakahori, Y., Matsushita, I., Abe, T., Nagai, R., Yazaki, Y.Assignment of cardiac homeobox gene CSX to human chromosome 5q34. Genomics 27: 204-206, 1995. 3. Turbay D, Wechsler SB, Blanchard KM, Izumo S (January 1997). "Molecular cloning, chromosomal mapping, and characterization of the human cardiac-specific homeobox gene hCsx". Mol Med 2 (1): 86-96. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- NK2 Homeobox 5 (NKX2-5)
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别名
- NKX2-5
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背景
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Synonyms: Homeobox protein Nkx-2.5,Cardiac-specific homeobox,Homeobox protein CSX,Homeobox protein NK-2 homolog E,NKX2-5,CSX, NKX2.5, NKX2E,
Tissue Specificity: Expressed only in the heart.
Background: Homeobox protein Nkx-2.5, also known as NKX2E or CSX is a protein that in humans is encoded by the NKX2-5 gene. It is mapped to 5q35.1. Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. Nkx2.5 and Tbx5 ly bound to the promoter of the gene encoding cardiac-specific natriuretic peptide precursor type A (NPPA) in tandem, and both transcription factors showed synergistic activation. The cardiac homeobox protein Nkx2.5 is essential in cardiac development, and mutations in CSX (which encodes Nkx2.5) cause various congenital heart malformations.
Sequence Similarities: Belongs to the NK-2 homeobox family.
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分子量
- 35 kDa
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基因ID
- 1482
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UniProt
- P52952
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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