RBX1 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for RBX1 抗体 (C-Term) (ABIN3043566)
抗原
See all RBX1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- Anti-ROC1/RBX1 Antibody
-
序列
- NHAFHFHCIS RWLKTRQVCP LDNREWEFQK YGH
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
预测反应
- identical to the related mouse sequence.
-
产品特性
- Anti-ROC1/RBX1 Antibody. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human ROC1, identical to the related mouse sequence.
-
亚型
- IgG
-
-
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 74-108), (C-Term) antibody
RBX1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB48352 unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 1-108) antibodyRBX1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 1-108) antibodyRBX1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) antibodyRBX1 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB950 unconjugated Recombinant Antibody
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) antibodyKD Validated RBX1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB7170 unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 1-108) antibodyRBX1 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 1859CT866-7-47 unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (C-Term) antibodyRBX1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 1-50) antibodyRBX1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 小鸡, 马 WB, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 1-100) antibodyRBX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Western blot, 0.1-0.5 μg/mL, Mouse, Rat Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
-
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- RBX1 (Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1))
-
别名
- RBX1
-
背景
-
Background: RING-box protein 1, also known as ROC1, is a protein that in humans is encoded by the RBX1 gene. This gene is mapped to chromosome 22q13.2 based on an alignment of the RBX1 sequence with the genomic sequence. ROC1 is recruited by cullin-1 to form a quaternary SCF (HOS)-ROC1 holoenzyme (with SKP1 and the BTRCP homolog HOS). SCF (HOS)-ROC1 binds IKK-beta-phosphorylated I-kappa-B-alpha and catalyzes its ubiquitination in the presence of ubiquitin, E1, and CDC34. Conclusively, ROC1 plays a unique role in the ubiquitination reaction by heterodimerizing with cullin-1 to catalyze ubiquitin polymerization.
Gene Full Name: ring-box 1
-
分子量
- 15 kDa
-
基因ID
- 9978
-
UniProt
- P62877
-
途径
- Cell Division Cycle, M Phase, SARS-CoV-2 Protein Interactome
抗原
-
