DLG1 抗体 (AA 1-165)
Quick Overview for DLG1 抗体 (AA 1-165) (ABIN3043562)
抗原
See all DLG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-165
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原理
- Anti-SAP97/DLG1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-SAP97/DLG1 Antibody Picoband® (ABIN3043562). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SAP97 recombinant protein (Position: M1-A165). Human SAP97 shares 89.7% and 84.2% amino acid (aa) sequence identity with mouse and rat SAP97, respectively.
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亚型
- IgG
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anti-Discs, Large Homolog 1 (DLG1) (AA 662-773) antibody
DLG1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 1 (DLG1) (AA 1-90) antibodyDLG1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-Discs, Large Homolog 1 (DLG1) (Internal Region) antibodyDLG1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 1 (DLG1) (AA 1-190) antibodyDLG1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 1 (DLG1) (AA 643-673) antibodyDLG1 适用: 人 WB 宿主: 兔 Polyclonal RB53955 unconjugated
anti-Discs, Large Homolog 1 (DLG1) (Internal Region) antibodyVerified DLG1 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Discs, Large Homolog 1 (DLG1) (AA 1-90) antibodyDLG1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-Discs, Large Homolog 1 (DLG1) (AA 1-90) antibodyDLG1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B12 unconjugated
anti-Discs, Large Homolog 1 (DLG1) (AA 115-133) antibodyDLG1 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Müller BM, Kistner U, Veh RW et al. (March 1995). "Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein". J. Neurosci. 15 (3 Pt 2): 2354-66. 2. umbaugh G, Sia GM, Garner CC, Huganir RL (June 2003). "Synapse-associated protein-97 isoform-specific regulation of surface AMPA receptors and synaptic function in cultured neurons". J. Neurosci. 23 (11): 4567-76. 3. Sans N, Racca C, Petralia RS, Wang YX, McCallum J, Wenthold RJ (October 2001). "Synapse-associated protein 97 selectively associates with a subset of AMPA receptors early in their biosynthetic pathway". J. Neurosci. 21 (19): 7506-16. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- DLG1 (Discs, Large Homolog 1 (DLG1))
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别名
- DLG1
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背景
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Synonyms: Disks large homolog 1,Synapse-associated protein 97,SAP-97,SAP97,hDlg,DLG1,
Tissue Specificity: Abundantly expressed in atrial myocardium (at protein level). Expressed in lung fibroblasts, cervical epithelial and B-cells (at protein level). Widely expressed, with isoforms displaying different expression profiles. .
Background: Disks large homolog 1 (DLG1), also known as synapse-associated protein 97 or SAP97, is a protein that in humans is encoded by the SAP97 gene. SAP97 is expressed throughout the body in epithelial cells, including the kidney and brain. There is some evidence that SAP97 regulates cell-to-cell adhesion during cell death, and may interact with HPV. In the brain, SAP97's function is involved in the trafficking of transmembrane receptors from the ER to the plasma membrane. SAP97's function has been investigated by reducing its expression by knockout or increasing its expression heterologously. Mice in which the SAP97 gene has been knocked out die perinatally, have a cleft palate, and deficiencies in renal function. Overexpression of SAP97 in mammalian neurons leads to increased synaptic strength.
Sequence Similarities: Belongs to the MAGUK family.
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分子量
- 130 kDa
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基因ID
- 1739
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UniProt
- Q12959
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途径
- Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response
抗原
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