Ectodysplasin A 抗体 (AA 30-391)
(1 reference)Quick Overview for Ectodysplasin A 抗体 (AA 30-391) (ABIN3043548)
抗原
See all Ectodysplasin A (EDA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-391
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原理
- Anti-EDA Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-EDA Antibody Picoband® (ABIN3043548). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human EDA recombinant protein (Position: A30-S391). Human EDA shares 95% amino acid (aa) sequence identity with mouse EDA.
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亚型
- IgG
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anti-Ectodysplasin A (EDA) (AA 131-230) antibody
EDA 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ectodysplasin A (EDA) (AA 101-200) antibodyEDA 适用: 人, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ectodysplasin A (EDA) (AA 47-76), (N-Term) antibodyEDA 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB13883 unconjugated
anti-Ectodysplasin A (EDA) (AA 245-391) antibodyEDA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B3 unconjugated
anti-Ectodysplasin A (EDA) (AA 245-391) antibodyEDA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E12 unconjugated
anti-Ectodysplasin A (EDA) (AA 218-267) antibodyEDA 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 小鸡, Pig, Bat, 斑马鱼, 猴, 非洲爪蟾, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Ectodysplasin A (EDA) (AA 252-301) antibodyEDA 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔, 小鸡, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ectodysplasin A (EDA) antibodyEDA 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
anti-Ectodysplasin A (EDA) (Middle Region) antibodyEDA 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. Bayes, M., Hartung, A. J., Ezer, S., Pispa, J., Thesleff, I., Srivastava, A. K., Kere, J. The anhidrotic ectodermal dysplasia gene (EDA) undergoes alternative splicing and encodes ectodysplasin-A with deletion mutations in collagenous repeats. Hum. Molec. Genet. 7: 1661-1669, 1998. 2. Kere J, Srivastava AK, Montonen O, Zonana J, Thomas N, Ferguson B, Munoz F, Morgan D, Clarke A, Baybayan P, Chen EY, Ezer S, Saarialho-Kere U, de la Chapelle A, Schlessinger D (Sep 1996). "X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein". Nat Genet 13 (4): 409-16. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "X-irradiation for inhibiting glial scar formation in injured spinal cord." in: Neural regeneration research, Vol. 8, Issue 17, pp. 1582-9, (2014) (PubMed).
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: "X-irradiation for inhibiting glial scar formation in injured spinal cord." in: Neural regeneration research, Vol. 8, Issue 17, pp. 1582-9, (2014) (PubMed).
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- Ectodysplasin A (EDA)
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别名
- EDA
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背景
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Synonyms: Ectodysplasin-A,Ectodermal dysplasia protein,EDA protein,Ectodysplasin-A, membrane form,Ectodysplasin-A, secreted form,EDA,ED1, EDA2,
Tissue Specificity: Not abundant, expressed in specific cell types of ectodermal (but not mesodermal) origin of keratinocytes, hair follicles, sweat glands. Also in adult heart, liver, muscle, pancreas, prostate, fetal liver, uterus, small intestine and umbilical chord. .
Background: Ectodysplasin-A is a protein that in humans is encoded by the EDA gene. It is mapped to Xq13.1. The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia.
Sequence Similarities: Belongs to the tumor necrosis factor family.
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分子量
- 43 kDa
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基因ID
- 1896
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UniProt
- Q92838
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途径
- Tube Formation
抗原
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