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Adiponectin Receptor 1 抗体 (N-Term)

This anti-Adiponectin Receptor 1 antibody is a 兔 多克隆 antibody detecting Adiponectin Receptor 1 in WB, ICC 和 IF. Suitable for 人 和 大鼠.
产品编号 ABIN3043520
发货至: 中国

Quick Overview for Adiponectin Receptor 1 抗体 (N-Term) (ABIN3043520)

抗原

See all Adiponectin Receptor 1 (ADIPOR1) 抗体
Adiponectin Receptor 1 (ADIPOR1)

适用

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人, 大鼠

宿主

  • 92
  • 6
  • 3

克隆类型

  • 84
  • 16
多克隆

标记

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  • 9
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  • 1
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  • 1
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This Adiponectin Receptor 1 antibody is un-conjugated

应用范围

  • 70
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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 11
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    • 4
    • 4
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    • 1
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    AA 51-78, N-Term

    原理

    Anti-Adiponectin Receptor 1/ADIPOR1 Antibody Picoband®

    序列

    EQTCPVPQEE EEEVRVLTLP LQAHHAME

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Adiponectin Receptor 1/ADIPOR1 Antibody Picoband® (ABIN3043520). Tested in IF, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human ADIPOR1, different from the related mouse sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    1. "Entrez Gene: ADIPOR1 adiponectin receptor 1" 2. Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, Sugiyama T, Miyagishi M, Hara K, Tsunoda M, Murakami K, Ohteki T, Uchida S, Takekawa S, Waki H, Tsuno NH, Shibata Y, Terauchi Y, Froguel P, Tobe K, Koyasu S, Taira K, Kitamura T, Shimizu T, Nagai R, Kadowaki T (June 2003). "Cloning of adiponectin receptors that mediate antidiabetic metabolic effects". Nature 423 (6941): 762-9.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Adiponectin Receptor 1 (ADIPOR1)

    别名

    ADIPOR1

    背景

    Synonyms: Adiponectin receptor protein 1,Progestin and adipoQ receptor family member I,ADIPOR1,PAQR1 , TESBP1A,CGI-45,

    Tissue Specificity: Widely expressed (PubMed:16044242). Highly expressed in heart and skeletal muscle (PubMed:12802337). Expressed at intermediate level in brain, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes (PubMed:12802337). Weakly expressed in colon, thymus and small intestine (PubMed:12802337). .

    Background: ADIPOR1 is known as Adiponectin receptor protein 1. This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene.

    Sequence Similarities: Belongs to the ADIPOR family.

    分子量

    43 kDa

    UniProt

    Q96A54

    途径

    AMPK Signaling
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