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BIK 抗体 (AA 1-123)

Name: BIK 抗体 (AA 1-123)
SKU: ABIN3043509
Availability: OutOfStock

BIK 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 1-123) antibody (ABIN3043509) (BIK 抗体 (AA 1-123))

IHC (p)

4 images

产品编号 ABIN3043509

发货至: 中国

Datasheet as PDF

抗原 See all BIK 抗体

BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
抗原表位
19

8

7

2

2

2

2

2

1

1

1

1

1

1

1

1
AA 1-123

适用

人, 小鼠, 大鼠
宿主
47

2
兔
Compatible Secondaries
克隆类型
47

2
多克隆
标记
32

3

2

2

2

2

1

1

1

1

1

1
This BIK antibody is un-conjugated
应用范围
39

30

29

13

11

4

3

3

2

2

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

原理

Anti-Bik Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Bik Antibody Picoband® (ABIN3043509). Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Bik recombinant protein (Position: M1-R123). Human Bik shares 42.3% amino acid (aa) sequence identity with mouse Bik.

亚型

IgG

Top Product

Discover our top product BIK Primary Antibody
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) antibody
BIK 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 1-123) antibody
BIK 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 37-136) antibody
BIK 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4G12 unconjugated

anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (N-Term) antibody
BIK 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (pThr33) antibody
BIK 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 39-74) antibody
BIK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3381 unconjugated

anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (pThr33) antibody
BIK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 37-136) antibody
BIK 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4G12 unconjugated

anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 18-67) antibody
BIK 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (BH3 Domain) antibody
BIK 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Rat
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human
Immunocytochemistry, 0.5-1 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human1. "Entrez Gene: BIK BCL2-interacting killer (apoptosis-inducing)". 2. Boyd JM, Gallo GJ, Elangovan B, Houghton AB, Malstrom S, Avery BJ, Ebb RG, Subramanian T, Chittenden T, Lutz RJ (Dec 1995). "Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins". Oncogene 11 (9): 1921-8. 3. Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP (Dec 1999). "The DNA sequence of human chromosome 22".Nature 402 (6761): 489-95.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

别名

BIK (BIK 产品)

背景

Synonyms: Bcl-2-interacting killer,Apoptosis inducer NBK,BIP1,BP4,BIK,NBK,
Tissue Specificity: Expressed in heart, brain, liver and prostate, but not in kidney, lung, adrenal, aorta and pituitary. Within the prostate, expressed in the apex, base, periurethral and lateral lobe. Isoform 4 is the most abundant isoform expressed in the prostate with high levels also detected in liver and heart. .
Background: Bcl-2-interacting killer is a protein that in humans is encoded by the BIK gene. This gene is mapped to 22q13.31. The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.

分子量

22 kDa

基因ID

638

UniProt

Q13323

途径

Positive Regulation of Endopeptidase Activity