BIK 抗体 (AA 1-123)
Quick Overview for BIK 抗体 (AA 1-123) (ABIN3043509)
抗原
See all BIK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-123
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原理
- Anti-Bik Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Bik Antibody Picoband® (ABIN3043509). Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Bik recombinant protein (Position: M1-R123). Human Bik shares 42.3% amino acid (aa) sequence identity with mouse Bik.
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亚型
- IgG
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anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) antibody
BIK 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 1-123) antibodyBIK 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 37-136) antibodyBIK 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4G12 unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (pThr33) antibodyBIK 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (N-Term) antibodyBIK 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 39-74) antibodyBIK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3381 unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (pThr33) antibodyBIK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 37-136) antibodyBIK 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4G12 unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 18-67) antibodyBIK 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (BH3 Domain) antibodyBIK 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Rat
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human
Immunocytochemistry, 0.5-1 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. "Entrez Gene: BIK BCL2-interacting killer (apoptosis-inducing)". 2. Boyd JM, Gallo GJ, Elangovan B, Houghton AB, Malstrom S, Avery BJ, Ebb RG, Subramanian T, Chittenden T, Lutz RJ (Dec 1995). "Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins". Oncogene 11 (9): 1921-8. 3. Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP (Dec 1999). "The DNA sequence of human chromosome 22".Nature 402 (6761): 489-95. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
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别名
- BIK
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背景
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Synonyms: Bcl-2-interacting killer,Apoptosis inducer NBK,BIP1,BP4,BIK,NBK,
Tissue Specificity: Expressed in heart, brain, liver and prostate, but not in kidney, lung, adrenal, aorta and pituitary. Within the prostate, expressed in the apex, base, periurethral and lateral lobe. Isoform 4 is the most abundant isoform expressed in the prostate with high levels also detected in liver and heart. .
Background: Bcl-2-interacting killer is a protein that in humans is encoded by the BIK gene. This gene is mapped to 22q13.31. The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.
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分子量
- 22 kDa
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基因ID
- 638
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UniProt
- Q13323
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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