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CD8 alpha 抗体 (AA 22-187)

Name: CD8 alpha 抗体 (AA 22-187)
SKU: ABIN3043499
Availability: OutOfStock

CD8A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

IHC(P): Human Tonsil Tissue (CD8 alpha 抗体 (AA 22-187))

IHC

Anti- CD 8 alpha Picoband antibody, Western blotting All lanes: Anti CD 8 alpha at 0. (CD8 alpha 抗体 (AA 22-187))

3 images

(3 references)

产品编号 ABIN3043499

发货至: 中国

Datasheet as PDF

抗原 See all CD8 alpha (CD8A) 抗体

CD8 alpha (CD8A) (CD8a Molecule (CD8A))
抗原表位
16

16

10

9

9

9

9

7

6

6

5

5

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 22-187
适用
168

107

40

37

11

7

3

2

2

2

2

2

2

2

2

1

1
人
宿主
125

123

89

1
兔
Compatible Secondaries
克隆类型
235

99

1
多克隆
标记
122

38

29

24

23

8

6

6

6

5

5

5

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This CD8 alpha antibody is un-conjugated
应用范围
263

106

90

66

52

45

25

19

15

14

14

9

8

7

6

6

5

3

3

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for T-cell surface glycoprotein CD8 alpha chain(CD8A) detection. Tested with WB, IHC-P in Human.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for T-cell surface glycoprotein CD8 alpha chain(CD8A) detection. Tested with WB, IHC-P in Human.
Gene Name: CD8a molecule
Protein Name: T-cell surface glycoprotein CD8 alpha chain

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human CD8 alpha recombinant protein (Position: S22-A187). Human CD8 alpha shares 49% and 47% amino acid (aa) sequence identity with mouse and rat CD8 alpha, respectively.

亚型

IgG

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anti-CD8a Molecule (CD8A) antibody
CD8A 适用: 小鼠 FACS, IP, IHC (fro), IHC (p), ICC, Func 宿主: 大鼠 Monoclonal 53-6-7 unconjugated

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anti-CD8a Molecule (CD8A) antibody
CD8A 适用: 人 IHC, StM, ISt 宿主: 小鼠 Monoclonal C8-468 unconjugated

anti-CD8a Molecule (CD8A) (N-Term) antibody
CD8A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CD8a Molecule (CD8A) (C-Term) antibody
CD8A 适用: 人 FACS, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for CD8 alpha is approximately 0.2 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Xu, Chen, Zhao, Huang, Duan, Tong, Zhang, Li, Chang, Chen: "The CD8? gene in duck (Anatidae): cloning, characterization, and expression during viral infection." in: Molecular biology reports, Vol. 42, Issue 2, pp. 431-9, (2015) (PubMed).

Xu, Tan, Wang, Wang, Li, Wu, Chen, Wu, Tan: "Elevated survivin expression in peripheral blood mononuclear cells is central to collateral formation in coronary chronic total occlusion." in: International journal of molecular medicine, Vol. 35, Issue 6, pp. 1501-10, (2015) (PubMed).

Zhang, Chen, Lao, Huang: "Effect of Hejie decoction on T cell immune state of chronic hepatitis B patients." in: World journal of gastroenterology, Vol. 10, Issue 10, pp. 1436-9, (2005) (PubMed).
抗原

CD8 alpha (CD8A) (CD8a Molecule (CD8A))

别名

CD8A (CD8A 产品)

别名

cd8 antibody, LOC100136450 antibody, BB154331 antibody, Ly-2 antibody, Ly-35 antibody, Ly-B antibody, Lyt-2 antibody, zgc:136643 antibody, CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody, RHACD8-4 antibody, CD8a molecule antibody, uncharacterized LOC100125537 antibody, CD8 alpha antibody, CD8 antigen, alpha chain antibody, T-cell surface glycoprotein CD8 alpha chain antibody, Cd8a antibody, LOC100125537 antibody, LOC100136450 antibody, CD8A antibody, cd8a antibody, LOC100126556 antibody

背景

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. It is mapped to 2p11.2. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene also encodes the CD8 alpha chain isoforms.

Synonyms: alpha polypeptide (p32) antibody|CD 8a antibody|CD8 alpha chain antibody|CD8 antibody|CD8 antigen alpha chain antibody|CD8 antigen alpha polypeptide antibody|CD8 antigen alpha polypeptide (p32) antibody|CD8a antibody|CD8a antigen antibody|CD8a molecule antibody|CD8A_HUMAN antibody|Leu 2 antibody|Leu2 antibody|Leu2 T lymphocyte antigen antibody|Ly3 antibody|LYT3 antibody|MAL antibody|OKT8 T cell antigen antibody|OTTHUMP00000160760 antibody|OTTHUMP00000160764 antibody|OTTHUMP00000203528 antibody|OTTHUMP00000203721 antibody|p32 antibody|T cell antigen Leu2 antibody|T cell co receptor antibody|T cell coreceptor antibody|T cell surface glycoprotein CD8 alpha chain antibody|T lymphocyte differentiation antigen T8/Leu 2 antibody|T lymphocyte differentiation antigen T8/Leu2 antibody|T-cell surface glycoprotein CD8 alpha chain antibody|T-lymphocyte differentiation antigen T8/Leu-2 antibody|T8 T cell antigen antibody|T8/Leu-2 T-lymphocyte differentiation antigen antibody

基因ID

925

UniProt

P01732

途径

TCR Signaling