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CCL7 抗体 (AA 24-97)

This anti-CCL7 antibody is a 兔 多克隆 antibody detecting CCL7 in WB 和 ELISA. Suitable for 小鼠.
产品编号 ABIN3043479
发货至: 中国
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Quick Overview for CCL7 抗体 (AA 24-97) (ABIN3043479)

抗原

See all CCL7 抗体
CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

适用

  • 67
  • 14
  • 7
  • 1
  • 1
  • 1
小鼠

宿主

  • 41
  • 31
  • 12
  • 1

克隆类型

  • 55
  • 30
多克隆

标记

  • 41
  • 14
  • 7
  • 7
  • 6
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CCL7 antibody is un-conjugated

应用范围

  • 57
  • 45
  • 19
  • 12
  • 10
  • 8
  • 6
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-97

    原理

    Anti-MCP3/CCL7 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-MCP3/CCL7 Antibody (ABIN3043479). Tested in ELISA, WB applications. This antibody reacts with Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse MCP3 recombinant protein (Position: Q24-P97). Mouse MCP3 shares 60% and 95% amino acid (aa) sequences identity with human and rat MCP3, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, -
    ELISA, 0.1-0.5 μg/mL, -

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

    别名

    CCL7

    背景

    Synonyms: C-C motif chemokine 7,Intercrine/chemokine MARC,Monocyte chemoattractant protein 3,Monocyte chemotactic protein 3,MCP-3,Protein FIC,Small-inducible cytokine A7,Ccl7,Fic, Mcp3, Scya7,

    Tissue Specificity: Found as a hybrid receptor with INSR in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Expressed in a variety of tissues. Overexpressed in tumors, including melanomas, cancers of the colon, pancreas prostate and kidney. .

    Background: Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). It belongs to the C-C chemokine family. By fluorescence in situ hybridization, MCP3 gene is mapped to chromosome 17q11.2-q12. MCP3 was identified as a physiologic substrate of gelatinase A. Cleaved MCP3 binds to CC-chemokine receptors-1, -2, and -3, but no longer induces calcium fluxes or promotes chemotaxis, and instead acts as a general chemokine antagonist that dampens inflammation, it has been found that matrix metalloproteinases are both effectors and regulators of the inflammatory response.

    Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.

    分子量

    36 kDa

    基因ID

    20306

    UniProt

    Q03366
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