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- 抗原 See all CCL5 抗体
- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
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抗原表位
- AA 26-91
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CCL5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Rabbit IgG polyclonal antibody for C-C motif chemokine 5(CCL5) detection. Tested with WB, ELISA in Human.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for C-C motif chemokine 5(CCL5) detection. Tested with WB, ELISA in Human.
Gene Name: chemokine (C-C motif) ligand 5
Protein Name: C-C motif chemokine 5 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived human RANTES recombinant protein (Position: Y26-S91). Human RANTES shares 83.3% amino acid (aa) sequence identity with both mouse and rat RANTES.
- 亚型
- IgG
- Top Product
- Discover our top product CCL5 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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Different locations of RANTES and its receptors on mouse epididymal spermatozoa." in: Reproduction, fertility, and development, (2015) (PubMed).
: "Regulated upon activation normal T-cell expressed and secreted originating from the epididymis differentially associates with viable and defective spermatozoa." in: Fertility and sterility, Vol. 93, Issue 8, pp. 2661-7, (2010) (PubMed).
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Different locations of RANTES and its receptors on mouse epididymal spermatozoa." in: Reproduction, fertility, and development, (2015) (PubMed).
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- 抗原
- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
- 别名
- CCL5 (CCL5 产品)
- 背景
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Chemokine (C-C motif) ligand 5 (also CCL5) is a protein which in humans is encoded by the CCL5 gene. It is also known as RANTES. This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.
Synonyms: Beta chemokine RANTES precursor antibody|CCL 5 antibody|CCL5 antibody|CCL5_HUMAN antibody|Chemokine (C C motif) ligand 5 antibody| Chemokine CC Motif Ligand 5 antibody|D17S136E antibody|EoCP antibody|Eosinophil chemotactic cytokine antibody|MGC17164 antibody| RANTES(4-68) antibody|Regulated upon activation normally T expressed and presumably secreted antibody|SCYA 5 antibody|SCYA5 antibody| SIS delta antibody|SIS-delta antibody|SISd antibody|Small inducible cytokine A5 (RANTES) antibody|Small inducible cytokine A5 antibody|Small inducible cytokine subfamily A (Cys Cys) member 5 antibody|Small-inducible cytokine A5 antibody|T cell specific protein p288 antibody|T cell specific RANTES protein antibody|T cell-specific protein P228 antibody|T-cell-specific protein RANTES antibody| TCP 228 antibody|TCP228 antibody - 基因ID
- 6352
- UniProt
- P13501
- 途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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