OPA1 抗体 (C-Term)
-
- 抗原 See all OPA1 抗体
- OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))
-
抗原表位
- AA 919-955, C-Term
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This OPA1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Dynamin-like 120 kDa protein, mitochondrial(OPA1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- EDGEKKIKLL TGKRVQLAED LKKVREIQEK LDAFIEA
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
-
Rabbit IgG polyclonal antibody for Dynamin-like 120 kDa protein, mitochondrial(OPA1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: optic atrophy 1 (autosomal dominant)
Protein Name: Dynamin-like 120 kDa protein, mitochondrial - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human OPA1 (919-955aa EDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEA), different from the related mouse and rat sequences by one amino acid.
- 亚型
- IgG
- Top Product
- Discover our top product OPA1 Primary Antibody
-
anti-Optic Atrophy 1 (Autosomal Dominant) (OPA1) (AA 661-960) antibody
OPA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Optic Atrophy 1 (Autosomal Dominant) (OPA1) (AA 851-960) antibodyOPA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8A20 unconjugated
anti-Optic Atrophy 1 (Autosomal Dominant) (OPA1) (AA 651-750) antibodyOPA1 适用: 人, 小鼠, 大鼠, 小鸡, 兔 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Optic Atrophy 1 (Autosomal Dominant) (OPA1) (AA 183-418) antibodyOPA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Optic Atrophy 1 (Autosomal Dominant) (OPA1) (AA 1-960) antibodyOPA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Optic Atrophy 1 (Autosomal Dominant) (OPA1) (AA 1-960) antibodyOPA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Optic Atrophy 1 (Autosomal Dominant) (OPA1) (AA 183-351) antibodyOPA1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Optic Atrophy 1 (Autosomal Dominant) (OPA1) (AA 851-960) antibodyOPA1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1C10 unconjugated
anti-Optic Atrophy 1 (Autosomal Dominant) (OPA1) (AA 500-600), (Internal Region) antibodyOPA1 适用: 人, 小鼠, 大鼠, 小鸡 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
-
- 抗原
- OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))
- 别名
- OPA1 (OPA1 产品)
- 背景
-
Dynamin-like 120 kDa protein, mitochondrial is a protein that in humans is encoded by the OPA1 gene. It is mapped to 3q29. This protein regulates mitochondrial fusion and cristae structure in the inner mitochondrial membrane (IMM) and contributes to ATP synthesis and apoptosis. This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: Dynamin like 120 kDa protein antibody|Dynamin like 120 kDa protein, mitochondrial antibody|Dynamin-like 120 kDa protein, form S1 antibody|FLJ12460 antibody|Juvenile kjer type optic atrophy antibody|KIAA0567 antibody|KJER type antibody|Large GTP binding protein antibody|largeG antibody|MGM1 antibody|Mitochondrial dynamin like 120 kDa protein antibody|Mitochondrial dynamin like GTPase antibody| NPG antibody|NTG antibody|OAK antibody|OPA 1 antibody|opa1 antibody|OPA1 gene antibody|OPA1_HUMAN antibody|Optic atrophy 1 (autosomal dominant) antibody|OPTIC ATROPHY 1 antibody|Optic atrophy 1 gene protein antibody|Optic atrophy 1 homolog (human) antibody| Optic atrophy protein 1 antibody|Optic atrophy protein 1 homolog antibody| - 基因ID
- 4976
- UniProt
- O60313
- 途径
- Tube Formation
-
