NMI 抗体 (AA 2-307)
Quick Overview for NMI 抗体 (AA 2-307) (ABIN3043451)
抗原
See all NMI 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-307
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原理
- Anti-N myc interactor/NMI Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-N myc interactor/NMI Antibody Picoband® (ABIN3043451). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NMI recombinant protein (Position: E2-E307). Human NMI shares 64% amino acid (aa) sequence identity with mouse NMI.
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亚型
- IgG
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anti-N-Myc (And STAT) Interactor (NMI) (AA 1-307) antibody
NMI 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-N-Myc (And STAT) Interactor (NMI) (AA 1-100) antibodyNMI 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 9D8 unconjugated
anti-N-Myc (And STAT) Interactor (NMI) (AA 1-100) antibodyNMI 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 9E8 unconjugated
anti-N-Myc (And STAT) Interactor (NMI) (AA 62-202) antibodyNMI 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Myc (And STAT) Interactor (NMI) (AA 1-307) antibodyNMI 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-N-Myc (And STAT) Interactor (NMI) antibodyNMI 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-N-Myc (And STAT) Interactor (NMI) (AA 1-101) antibodyNMI 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 9D8 unconjugated
anti-N-Myc (And STAT) Interactor (NMI) (AA 66-115) antibodyNMI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Myc (And STAT) Interactor (NMI) (AA 180-229) antibodyNMI 适用: 人, 大鼠, 小鼠, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Myc (And STAT) Interactor (NMI) (Middle Region) antibodyNMI 适用: 人, 大鼠, 小鼠, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Albihn A, et al. Camptothecin-induced apoptosis is enhanced by Myc and involves PKCdelta signaling. Int J Cancer, 2007 Oct 15. 2. Fillmore RA, et al. Nmi (N-Myc interactor) inhibits Wnt/beta-catenin signaling and retards tumor growth. Int J Cancer, 2009 Aug 1. 3. Lebrun SJ, et al. Interferon-induced upregulation and cytoplasmic localization of Myc-interacting protein Nmi. J Interferon Cytokine Res, 1998 Sep. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- NMI (N-Myc (And STAT) Interactor (NMI))
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别名
- NMI
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背景
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Synonyms: N-myc-interactor,Nmi,N-myc and STAT interactor,NMI,
Tissue Specificity: Expressed in all adult and fetal tissues except brain and skin. More abundant in fetal tissues especially liver.
Background: NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.
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分子量
- 35 kDa
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基因ID
- 9111
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UniProt
- Q13287
抗原
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