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- 抗原 See all rala 抗体
- rala (Ras-related Protein Ral-A (rala))
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抗原表位
- AA 165-203, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This rala antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Ras-related protein Ral-A(RALA) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- DKVFFDLMRE IRARKMEDSK EKNGKKKRKS LAKRIRERC
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Ras-related protein Ral-A(RALA) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: v-ral simian leukemia viral oncogene homolog A (ras related)
Protein Name: Ras-related protein Ral-A - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human RALA (165-203aa DKVFFDLMREIRARKMEDSKEKNGKKKRKSLAKRIRERC), identical to the related mouse and rat sequences.
- 亚型
- IgG
- Top Product
- Discover our top product rala Primary Antibody
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anti-Ras-related Protein Ral-A (rala) (AA 1-206) antibody
rala 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Ras-related Protein Ral-A (rala) (AA 71-203) antibodyrala 适用: 人, 小鼠, 猴 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 4G8B11 unconjugated
anti-Ras-related Protein Ral-A (rala) antibodyrala 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras-related Protein Ral-A (rala) (Center) antibodyrala 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ras-related Protein Ral-A (rala) (AA 1-203) antibodyrala 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras-related Protein Ral-A (rala) antibodyrala 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Ras-related Protein Ral-A (rala) (pSer194) antibodyrala 适用: 人 ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3E6 unconjugated
anti-Ras-related Protein Ral-A (rala) (C-Term) antibodyrala 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras-related Protein Ral-A (rala) (AA 1-206) antibodyrala 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras-related Protein Ral-A (rala) (AA 1-206) antibodyrala 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- rala (Ras-related Protein Ral-A (rala))
- 别名
- RALA (rala 产品)
- 别名
- 3010001O15Rik antibody, AW322615 antibody, Ral antibody, Rasl1 antibody, RAL antibody, v-ral simian leukemia viral oncogene A (ras related) antibody, RAS like proto-oncogene A antibody, Rala antibody, RALA antibody
- 背景
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Ras-related protein Ral-A (RalA) is a protein that in humans is encoded by the RALA gene on chromosome 7. This protein is one of two isoforms of the Ral protein, the other being RalB, and part of the Ras GTPase family. As a Ras GTPase, RalA functions as a molecular switch that becomes active when bound to GTP and inactive when bound to GDP. It can be activated by RalGEFs and, in turn, activate effectors in signal transduction pathways leading to biological outcomes. Additionally, Ral proteins have been associated with the progression of several cancers, including bladder cancer and prostate cancer. While the above functions appear to be shared between the two Ral isoforms, their differential subcellular localizations result in their differing involvement in certain biological processes. In particular, RalA is more involved in anchorage-independent cell growth, vesicle trafficking, and cytoskeletal organization. Moreover, RalA specifically interacts with Exo84 and Sec5 to regulate transport of membrane proteins in polarized epithelial cells and GLUT4 to the plasma membrane, as well as mitochondrial fission for cell division.
Synonyms: MGC48949 antibody|Ral a antibody|Ral A protein antibody|RAL antibody|RALA antibody|RALA_HUMAN antibody|Ras family small GTP binding protein RALA antibody|RAS like protein A antibody|Ras related protein RalA antibody|Ras-related protein Ral-A antibody|v ral simian leukemia viral oncogene homolog A (ras related) antibody|v ral simian leukemia viral oncogene homolog A antibody - 基因ID
- 5898
- UniProt
- P11233
- 途径
- Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
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