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- 抗原 See all PRC1 抗体
- PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
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抗原表位
- AA 1-233
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Anti-PRC1 Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-PRC1 Antibody Picoband® (ABIN3043445). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human PRC1 recombinant protein (Position: M1-E233). Human PRC1 shares 85% amino acid (aa) sequence identity with mouse PRC1.
- 亚型
- IgG
- Top Product
- Discover our top product PRC1 Primary Antibody
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anti-Protein Regulator of Cytokinesis 1 (PRC1) (AA 351-620) antibody
PRC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Regulator of Cytokinesis 1 (PRC1) (AA 1-620) antibodyPRC1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B10-1F9 unconjugated
anti-Protein Regulator of Cytokinesis 1 (PRC1) (Internal Region) antibodyPRC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Regulator of Cytokinesis 1 (PRC1) (pThr481) antibodyPRC1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Regulator of Cytokinesis 1 (PRC1) (AA 460-520) antibodyPRC1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Regulator of Cytokinesis 1 (PRC1) (AA 1-150) antibodyPRC1 适用: 人 WB 宿主: 小鼠 Monoclonal 6G2 unconjugated
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- 应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: PRC1 protein regulator of cytokinesis 1". 2. Hartz, P. A. Personal Communication. Baltimore, Md. 2/1/2005. 3. Jiang W, Jimenez G, Wells NJ, Hope TJ, Wahl GM, Hunter T, Fukunaga R (1998). "PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis.". Mol. Cell. 2 (6): 877-85. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- 抗原
- PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
- 别名
- PRC1 (PRC1 产品)
- 背景
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Synonyms: Protein regulator of cytokinesis 1 ,PRC1 ,
Tissue Specificity: Overexpressed in bladder cancer cells (PubMed:17409436). .
Background: Protein Regulator of cytokinesis 1 (PRC1) is a protein that in humans is encoded by the PRC1 gene and is involved in cytokinesis. This gene is mapped to chromosome 15q26.1 based on an alignment of the PRC1 sequence with the genomic sequence. PRC1 protein is expressed at relatively high levels during S and G2/M phases of the cell cycle before dropping dramatically after mitotic exit and entrance into G1 phase. It is located in the nucleus during interphase, becomes associated with the mitotic spindle in a highly dynamic manner during anaphase, and localizes to the cell midbody during cytokinesis. And this protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants.
- 分子量
- 75 kDa, 80 kDa
- 基因ID
- 9055
- UniProt
- O43663
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