SGCA 抗体 (AA 24-387)
Quick Overview for SGCA 抗体 (AA 24-387) (ABIN3043432)
抗原
See all SGCA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-387
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原理
- Anti-alpha Sarcoglycan/SGCA Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-alpha Sarcoglycan/SGCA Antibody Picoband® (ABIN3043432). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SGCA recombinant protein (Position: Q24-H387). Human SGCA shares 90.7% amino acid (aa) sequence identity with mouse SGCA.
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亚型
- IgG
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anti-Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA) (AA 24-290) antibody
SGCA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA) (AA 60-290) antibodySGCA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA) (AA 26-133) antibodySGCA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA) (Internal Region) antibodySGCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA) antibodySGCA 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
1. "Entrez Gene: SGCA sarcoglycan, alpha (50 kDa dystrophin-associated glycoprotein)". 2. McNally EM, Yoshida M, Mizuno Y, Ozawa E, Kunkel LM (Nov 1994). "Human adhalin is alternatively spliced and the gene is located on chromosome 17q21". Proc Natl Acad Sci U S A 91 (21): 9690-4. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SGCA (Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA))
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别名
- SGCA
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背景
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Synonyms: Alpha-sarcoglycan,Alpha-SG,50 kDa dystrophin-associated glycoprotein,50DAG,Adhalin,Dystroglycan-2,SGCA,ADL, DAG2,
Tissue Specificity: Most strongly expressed in skeletal muscle. Also expressed in cardiac muscle and, at much lower levels, in lung. In the fetus, most abundant in cardiac muscle and, at lower levels, in lung. Also detected in liver and kidney. Not expressed in brain.
Background: Alpha-sarcoglycan is a protein that in humans is encoded by the SGCA gene. This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
Sequence Similarities: Belongs to the sarcoglycan alpha/epsilon family.
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分子量
- 43 kDa
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基因ID
- 6442
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UniProt
- Q16586
抗原
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