RRM2 抗体 (N-Term)
(1 reference)-
- 抗原 See all RRM2 抗体
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
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抗原表位
- AA 1-33, N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RRM2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- Anti-RRM2 Antibody Picoband®
- 序列
- MLSLRVPLAP ITDPQQLQLS PLKGLSLVDK ENT
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-RRM2 Antibody Picoband® (ABIN3043425). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human RRM2, different from the related mouse and rat sequences by eight amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product RRM2 Primary Antibody
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anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-110) antibody
RRM2 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-389) antibodyRRM2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (Regulatory Subunit) antibodyKO Validated RRM2 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (C-Term) antibodyRRM2 适用: 人, 小鼠, 大鼠, 非洲爪蟾 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-389) antibodyRRM2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (C-Term) antibodyRRM2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-111) antibodyRRM2 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) antibodyRRM2 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-389) antibodyRRM2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) antibodyRRM2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: ribonucleotide reductase M2". 2. Pavloff, N., Rivard, D., Masson, S., Shen, S.-H., Mes-Masson, A.-M. Sequence analysis of the large and small subunits of human ribonucleotide reductase. DNA Seq. 2: 227-234, 1992. 3. Yang-Feng, T. L., Thelander, L., Lewis, W. H., Srinivasan, P. R., Francke, U. Gene localization of the ribonucleotide reductase M2 subunit and of related and co-amplified sequences on human and mouse chromosomes. (Abstract) Am. J. Hum. Genet. 39: A174 only, 1986. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Histone acetyltransferase inhibitor II induces apoptosis in glioma cell lines via the p53 signaling pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 33, pp. 108, (2015) (PubMed).
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: "Histone acetyltransferase inhibitor II induces apoptosis in glioma cell lines via the p53 signaling pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 33, pp. 108, (2015) (PubMed).
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- 抗原
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
- 别名
- RRM2 (RRM2 产品)
- 背景
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Synonyms: Ribonucleoside-diphosphate reductase subunit M2,1.17.4.1,Ribonucleotide reductase small chain,Ribonucleotide reductase small subunit,RRM2,RR2,
Tissue Specificity: Overexpressed in bladder cancer cells (PubMed:17409436). .
Background: Ribonucleoside-diphosphate reductase subunit M2, also known as ribonucleotide reductase small subunit, is an enzyme that in humans is encoded by the RRM2 gene. It is mapped to 2p25-p24. This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms which differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X.
- 分子量
- 50 kDa
- 基因ID
- 6241
- UniProt
- P31350
- 途径
- Mitotic G1-G1/S Phases
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