RRM2 抗体 (N-Term)
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北京 101111
Quick Overview for RRM2 抗体 (N-Term) (ABIN3043425)
抗原
See all RRM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-33, N-Term
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原理
- Anti-RRM2 Antibody
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序列
- MLSLRVPLAP ITDPQQLQLS PLKGLSLVDK ENT
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RRM2 Antibody (ABIN3043425). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human RRM2, different from the related mouse and rat sequences by eight amino acids.
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亚型
- IgG
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anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-110) antibody
RRM2 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-389) antibodyRRM2 适用: 人 WB, IF, IP, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (Regulatory Subunit) antibodyKO Validated RRM2 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (C-Term) antibodyRRM2 适用: 人, 小鼠, 大鼠, 非洲爪蟾 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (C-Term) antibodyRRM2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-111) antibodyRRM2 适用: 人 WB, ELISA, IF, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-389) antibodyRRM2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) antibodyRRM2 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M2 (RRM2) antibodyRRM2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4090 unconjugated Recombinant Antibody
anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-389) antibodyRRM2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Histone acetyltransferase inhibitor II induces apoptosis in glioma cell lines via the p53 signaling pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 33, pp. 108, (2015) (PubMed).
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: "Histone acetyltransferase inhibitor II induces apoptosis in glioma cell lines via the p53 signaling pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 33, pp. 108, (2015) (PubMed).
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- RRM2 (Ribonucleotide Reductase M2 (RRM2))
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别名
- RRM2
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背景
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Synonyms: Ribonucleoside-diphosphate reductase subunit M2,1.17.4.1,Ribonucleotide reductase small chain,Ribonucleotide reductase small subunit,RRM2,RR2,
Tissue Specificity: Overexpressed in bladder cancer cells (PubMed:17409436). .
Background: Ribonucleoside-diphosphate reductase subunit M2, also known as ribonucleotide reductase small subunit, is an enzyme that in humans is encoded by the RRM2 gene. It is mapped to 2p25-p24. This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms which differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X.
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分子量
- 45 kDa
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基因ID
- 6241
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UniProt
- P31350
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途径
- Mitotic G1-G1/S Phases
抗原
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