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RRM2 抗体 (N-Term)

Name: RRM2 抗体 (N-Term)
SKU: ABIN3043425
Availability: OutOfStock

This anti-RRM2 antibody is a 兔多克隆 antibody detecting RRM2 in WB 和 IHC. Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 1 publication.

Western Blotting (WB) image for anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-33), (N-Term) antibody (ABIN3043425) (RRM2 抗体 (N-Term))

Anti- RRM2 Picoband antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue (RRM2 抗体 (N-Term))

IHC

2 images

(1 reference)

产品编号 ABIN3043425

发货至: 中国

Quick Overview for RRM2 抗体 (N-Term) (ABIN3043425)

抗原

See all RRM2 抗体

RRM2 (Ribonucleotide Reductase M2 (RRM2))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This RRM2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product RRM2 Primary Antibody

抗原表位
15

9

2

2

2

2

1

1

1

1
AA 1-33, N-Term

原理

Anti-RRM2 Antibody Picoband®

序列

MLSLRVPLAP ITDPQQLQLS PLKGLSLVDK ENT

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-RRM2 Antibody Picoband® (ABIN3043425). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human RRM2, different from the related mouse and rat sequences by eight amino acids.

亚型

IgG
anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-110) antibody
RRM2 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 1E1 unconjugated

anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-389) antibody
RRM2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Ribonucleotide Reductase M2 (RRM2) (Regulatory Subunit) antibody
KO Validated RRM2 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Ribonucleotide Reductase M2 (RRM2) (C-Term) antibody
RRM2 适用: 人, 小鼠, 大鼠, 非洲爪蟾 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-111) antibody
RRM2 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E1 unconjugated

anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-389) antibody
RRM2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Ribonucleotide Reductase M2 (RRM2) (C-Term) antibody
RRM2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Ribonucleotide Reductase M2 (RRM2) antibody
RRM2 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Ribonucleotide Reductase M2 (RRM2) (AA 1-389) antibody
RRM2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Ribonucleotide Reductase M2 (RRM2) antibody
RRM2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

应用备注

Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: ribonucleotide reductase M2". 2. Pavloff, N., Rivard, D., Masson, S., Shen, S.-H., Mes-Masson, A.-M. Sequence analysis of the large and small subunits of human ribonucleotide reductase. DNA Seq. 2: 227-234, 1992. 3. Yang-Feng, T. L., Thelander, L., Lewis, W. H., Srinivasan, P. R., Francke, U. Gene localization of the ribonucleotide reductase M2 subunit and of related and co-amplified sequences on human and mouse chromosomes. (Abstract) Am. J. Hum. Genet. 39: A174 only, 1986.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Xu, Li, Tao, Li, Fang, Zhao, Li, Li, Wang, Feng, Pan: "Histone acetyltransferase inhibitor II induces apoptosis in glioma cell lines via the p53 signaling pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 33, pp. 108, (2015) (PubMed).
抗原

RRM2 (Ribonucleotide Reductase M2 (RRM2))

别名

RRM2

背景

Synonyms: Ribonucleoside-diphosphate reductase subunit M2,1.17.4.1,Ribonucleotide reductase small chain,Ribonucleotide reductase small subunit,RRM2,RR2,
Tissue Specificity: Overexpressed in bladder cancer cells (PubMed:17409436). .
Background: Ribonucleoside-diphosphate reductase subunit M2, also known as ribonucleotide reductase small subunit, is an enzyme that in humans is encoded by the RRM2 gene. It is mapped to 2p25-p24. This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms which differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X.

分子量

50 kDa

基因ID

6241

UniProt

P31350

途径

Mitotic G1-G1/S Phases