STXBP1 抗体 (N-Term)
Quick Overview for STXBP1 抗体 (N-Term) (ABIN3043413)
抗原
See all STXBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 184-216, N-Term
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原理
- Anti-Munc18-1/STXBP1 Antibody Picoband®
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序列
- KEYPAVRYRG EYKDNALLAQ LIQDKLDAYK ADD
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Munc18-1/STXBP1 Antibody Picoband® (ABIN3043413). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Munc18-1, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Syntaxin Binding Protein 1 (STXBP1) (AA 74-168) antibody
STXBP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 6D1 unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (C-Term) antibodyVerified STXBP1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 295-594) antibodySTXBP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 245-594) antibodySTXBP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 74-169) antibodySTXBP1 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6D1 unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) antibodySTXBP1 适用: 人, 小鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (C-Term) antibodySTXBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) antibodySTXBP1 适用: 人, 小鼠, 大鼠, Cow WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 1-603) antibodySTXBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 1-603) antibodySTXBP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. "Entrez Gene: STXBP1 syntaxin binding protein 1". 2. Fisher, R. J., Pevsner, J., Burgoyne, R. D. Control of fusion pore dynamics during exocytosis by Munc18. Science 291: 875-878, 2001. 3. Swanson DA, Steel JM, Valle D (Jun 1998). "Identification and characterization of the human ortholog of rat STXBP1, a protein implicated in vesicle trafficking and neurotransmitter release". Genomics 48 (3): 373-6. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- STXBP1 (Syntaxin Binding Protein 1 (STXBP1))
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别名
- STXBP1
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背景
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Synonyms: Syntaxin-binding protein 1,MUNC18-1,N-Sec1,Protein unc-18 homolog 1,Unc18-1,Protein unc-18 homolog A,Unc-18A,p67,STXBP1,UNC18A,
Tissue Specificity: Brain and spinal cord. Highly enriched in axons.
Background: Syntaxin-binding protein 1, also known as Munc18-1, is a protein that in humans is encoded by the STXBP1 gene. By fluorescence in situ hybridization, the STXBP1 gene is mapped to chromosome 9q34.1. This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.
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分子量
- 70 kDa
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基因ID
- 6812
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UniProt
- P61764
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途径
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
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