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MMP1 抗体 (Middle Region)

MMP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043405
发货至: 中国
  • 抗原 See all MMP1 抗体
    MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
    抗原表位
    • 15
    • 15
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 194-231, Middle Region
    适用
    • 122
    • 55
    • 51
    • 35
    • 16
    • 5
    • 4
    • 3
    • 1
    • 1
    宿主
    • 105
    • 23
    • 1
    克隆类型
    • 108
    • 21
    多克隆
    标记
    • 58
    • 13
    • 11
    • 10
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This MMP1 antibody is un-conjugated
    应用范围
    • 114
    • 60
    • 39
    • 39
    • 37
    • 29
    • 22
    • 16
    • 12
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Interstitial collagenase(MMP1) detection. Tested with WB in Human.
    序列
    DAHFDEDERW TNNFREYNLH RVAAHELGHS LGLSHSTD
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Interstitial collagenase(MMP1) detection. Tested with WB in Human.
    Gene Name: matrix metallopeptidase 1
    Protein Name: Interstitial collagenase
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human MMP1 (194-231aa DAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTD).
    亚型
    IgG
    Top Product
    Discover our top product MMP1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Wendan, Changzhu, Xuhong, Hongjing, Hong, Dongxia, Fang: "BMSCs Interactions with Adventitial Fibroblasts Display Smooth Muscle Cell Lineage Potential in Differentiation and Migration That Contributes to Neointimal Formation." in: Stem cells international, Vol. 2016, pp. 3196071, (2016) (PubMed).

    Zhang, Teng, Liu, Zhang, Liu: "Gene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasis." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 16, (2015) (PubMed).

    Deng, Ling, Liu, Zhao, Lv: "Decreased expression of matrix metalloproteinase-1 in the maternal umbilical serum, trophoblasts and decidua leads to preeclampsia." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 992-998, (2015) (PubMed).

    Fan, Chen, Ni, Wang, Sun, Chen, Zheng: "Expression of MMP-1/PAR-1 and patterns of invasion in oral squamous cell carcinoma as potential prognostic markers." in: OncoTargets and therapy, Vol. 8, pp. 1619-26, (2015) (PubMed).

    Xu, Zhang, Xu, Guo, Wang, Wu, Wang, Luo, Zhou: "Antiphotoaging effect of conditioned medium of dedifferentiated adipocytes on skin in vivo and in vitro: a mechanistic study." in: Stem cells and development, Vol. 24, Issue 9, pp. 1096-111, (2015) (PubMed).

    Zhang, Sun, Zhang, Ge, Liu, Zhao, Lu, Fan: "Norcantharidin inhibits tumor growth and vasculogenic mimicry of human gallbladder carcinomas by suppression of the PI3-K/MMPs/Ln-5?2 signaling pathway." in: BMC cancer, Vol. 14, pp. 193, (2014) (PubMed).

    Zhu, Sun, Zhang, Liu, Li, Fan: "Norcantharidin enhances TIMP?2 anti?vasculogenic mimicry activity for human gallbladder cancers through downregulating MMP?2 and MT1?MMP." in: International journal of oncology, Vol. 46, Issue 2, pp. 627-40, (2014) (PubMed).

    Yuan, Yang, Sun, Liu, Wang, Li, Man, Fu: "Effects of hydroxysafflor yellow A on proliferation and collagen synthesis of rat vascular adventitial fibroblasts induced by angiotensin II." in: International journal of clinical and experimental pathology, Vol. 7, Issue 9, pp. 5772-81, (2014) (PubMed).

    Man, Gao, Zhang, Liu, Yan, Huang, Liu: "Formosanin C-inhibited pulmonary metastasis through repression of matrix metalloproteinases on mouse lung adenocarcinoma." in: Cancer biology & therapy, Vol. 11, Issue 6, pp. 592-8, (2011) (PubMed).

    Liang, Pei, Zhang, Wang, Wang, Li: "The protective effects of long-term oral administration of marine collagen hydrolysate from chum salmon on collagen matrix homeostasis in the chronological aged skin of Sprague-Dawley male rats." in: Journal of food science, Vol. 75, Issue 8, pp. H230-8, (2011) (PubMed).

    Zhang, Ding, Shi, Li, Haom, Ke, Tang: "Effects of exogenous urotensin II on vascular remodelling after balloon injury." in: Clinical and experimental pharmacology & physiology, Vol. 37, Issue 4, pp. 477-81, (2010) (PubMed).

    Liu, Ahmed, Nantajit, Rosenthal, Hai, Li: "Therapeutic effects of alpha-lipoic acid on bleomycin-induced pulmonary fibrosis in rats." in: International journal of molecular medicine, Vol. 19, Issue 6, pp. 865-73, (2007) (PubMed).

    Yang, Xie, Geng, Luo, Han, Cheng: "Effect of Danshao Huaxian capsule on expression of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 in fibrotic liver of rats." in: World journal of gastroenterology, Vol. 11, Issue 32, pp. 4953-6, (2005) (PubMed).

  • 抗原
    MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
    别名
    MMP1 (MMP1 产品)
    别名
    CLG antibody, CLGN antibody, Mmp1a antibody, CG4859 antibody, Dm1-MMP antibody, Dmel\\CG4859 antibody, MMP-1 antibody, MMP1 antibody, Mmp 1 antibody, dMMP1 antibody, dm1-MMP antibody, dmmp1 antibody, l(2)k04809 antibody, mmp1 antibody, Mmp1 antibody, Mcol-A antibody, Mcola antibody, col4 antibody, mmp18 antibody, Clgn antibody, matrix metallopeptidase 1 antibody, Matrix metalloproteinase 1 antibody, matrix metalloproteinase 1 antibody, matrix metallopeptidase 1 (interstitial collagenase) antibody, matrix metallopeptidase 1a (interstitial collagenase) antibody, matrix metallopeptidase 1 S homeolog antibody, interstitial collagenase antibody, matrix metallopeptidase 8 L homeolog antibody, MMP1 antibody, Mmp1 antibody, RB11133 antibody, Mmp1a antibody, mmp1.S antibody, LOC100727966 antibody, mmp8.L antibody
    背景
    Matrix metalloproteinase-1 (MMP-1), also known as interstitial collagenase and fibroblast collagenase, is an enzyme that in humans is encoded by the MMP1 gene. MMP-1 was the first vertebrate collagenase both purified to homogeneity as a protein, and cloned as a cDNA. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. It is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

    Synonyms: 27 kDa interstitial collagenase antibody|CLG antibody|CLGN antibody|collagenase, fibroblast antibody|collagenase, interstitial antibody|Fibroblast collagenase antibody|Interstitial collagenase antibody|Matrix metallopeptidase 1 (interstitial collagenase) antibody|Matrix metalloprotease 1 antibody|Matrix Metalloproteinase 1 antibody|Matrix metalloproteinase-1 antibody|MMP 1 antibody|MMP-1 antibody|MMP1 antibody|MMP1_HUMAN antibody|OTTHUMP00000045866 antibody
    基因ID
    4312
    UniProt
    P03956
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