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MMP1 抗体 (Middle Region)

Name: MMP1 抗体 (Middle Region)
SKU: ABIN3043405
Availability: OutOfStock

Cited in 13+ publications. This 兔多克隆 anti-MMP1 antibody specifically detects MMP1 in WB. The antibody is reactive with 人 samples.

Western Blotting (WB) image for anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 194-231), (Middle Region) antibody (ABIN3043405) (MMP1 抗体 (Middle Region))

1 image

(13 references)

产品编号 ABIN3043405

发货至: 中国

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中国
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Quick Overview for MMP1 抗体 (Middle Region) (ABIN3043405)

抗原

See all MMP1 抗体

MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

适用

人

宿主

兔

克隆类型

多克隆

标记

This MMP1 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product MMP1 Primary Antibody

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AA 194-231, Middle Region

原理

Anti-MMP1 Antibody

序列

DAHFDEDERW TNNFREYNLH RVAAHELGHS LGLSHSTD

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-MMP1 Antibody (ABIN3043405). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human MMP1.

亚型

IgG
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) antibody
MMP1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 1-469) antibody
MMP1 适用: 人 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) antibody
MMP1 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6A5 unconjugated

anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 169-464) antibody
MMP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 20-280) antibody
MMP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (N-Term) antibody
MMP1 适用: 人, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (C-Term) antibody
MMP1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 1-469) antibody
MMP1 适用: 人 WB, IHC (p), PLA 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 317-347) antibody
MMP1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (C-Term) antibody
MMP1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Wendan, Changzhu, Xuhong, Hongjing, Hong, Dongxia, Fang: "BMSCs Interactions with Adventitial Fibroblasts Display Smooth Muscle Cell Lineage Potential in Differentiation and Migration That Contributes to Neointimal Formation." in: Stem cells international, Vol. 2016, pp. 3196071, (2016) (PubMed).

Zhang, Teng, Liu, Zhang, Liu: "Gene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasis." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 16, (2015) (PubMed).

Deng, Ling, Liu, Zhao, Lv: "Decreased expression of matrix metalloproteinase-1 in the maternal umbilical serum, trophoblasts and decidua leads to preeclampsia." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 992-998, (2015) (PubMed).

Fan, Chen, Ni, Wang, Sun, Chen, Zheng: "Expression of MMP-1/PAR-1 and patterns of invasion in oral squamous cell carcinoma as potential prognostic markers." in: OncoTargets and therapy, Vol. 8, pp. 1619-26, (2015) (PubMed).

Xu, Zhang, Xu, Guo, Wang, Wu, Wang, Luo, Zhou: "Antiphotoaging effect of conditioned medium of dedifferentiated adipocytes on skin in vivo and in vitro: a mechanistic study." in: Stem cells and development, Vol. 24, Issue 9, pp. 1096-111, (2015) (PubMed).

Zhang, Sun, Zhang, Ge, Liu, Zhao, Lu, Fan: "Norcantharidin inhibits tumor growth and vasculogenic mimicry of human gallbladder carcinomas by suppression of the PI3-K/MMPs/Ln-5?2 signaling pathway." in: BMC cancer, Vol. 14, pp. 193, (2014) (PubMed).

Zhu, Sun, Zhang, Liu, Li, Fan: "Norcantharidin enhances TIMP?2 anti?vasculogenic mimicry activity for human gallbladder cancers through downregulating MMP?2 and MT1?MMP." in: International journal of oncology, Vol. 46, Issue 2, pp. 627-40, (2014) (PubMed).

Yuan, Yang, Sun, Liu, Wang, Li, Man, Fu: "Effects of hydroxysafflor yellow A on proliferation and collagen synthesis of rat vascular adventitial fibroblasts induced by angiotensin II." in: International journal of clinical and experimental pathology, Vol. 7, Issue 9, pp. 5772-81, (2014) (PubMed).

Man, Gao, Zhang, Liu, Yan, Huang, Liu: "Formosanin C-inhibited pulmonary metastasis through repression of matrix metalloproteinases on mouse lung adenocarcinoma." in: Cancer biology & therapy, Vol. 11, Issue 6, pp. 592-8, (2011) (PubMed).

Liang, Pei, Zhang, Wang, Wang, Li: "The protective effects of long-term oral administration of marine collagen hydrolysate from chum salmon on collagen matrix homeostasis in the chronological aged skin of Sprague-Dawley male rats." in: Journal of food science, Vol. 75, Issue 8, pp. H230-8, (2011) (PubMed).

Zhang, Ding, Shi, Li, Haom, Ke, Tang: "Effects of exogenous urotensin II on vascular remodelling after balloon injury." in: Clinical and experimental pharmacology & physiology, Vol. 37, Issue 4, pp. 477-81, (2010) (PubMed).

Liu, Ahmed, Nantajit, Rosenthal, Hai, Li: "Therapeutic effects of alpha-lipoic acid on bleomycin-induced pulmonary fibrosis in rats." in: International journal of molecular medicine, Vol. 19, Issue 6, pp. 865-73, (2007) (PubMed).

Yang, Xie, Geng, Luo, Han, Cheng: "Effect of Danshao Huaxian capsule on expression of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 in fibrotic liver of rats." in: World journal of gastroenterology, Vol. 11, Issue 32, pp. 4953-6, (2005) (PubMed).
抗原

MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

别名

MMP1

背景

Synonyms: Interstitial collagenase,3.4.24.7,Fibroblast collagenase,Matrix metalloproteinase-1,MMP-1,22 kDa interstitial collagenase,27 kDa interstitial collagenase,MMP1,CLG,
Tissue Specificity: Colon, lymphocytes, breast, lung, spleen, testis, prostate, thyroid, gall bladder and heart.
Background: Matrix metalloproteinase-1 (MMP-1), also known as interstitial collagenase and fibroblast collagenase, is an enzyme that in humans is encoded by the MMP1 gene. MMP-1 was the first vertebrate collagenase both purified to homogeneity as a protein, and cloned as a cDNA. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. It is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

分子量

54 kDa

基因ID

4312

UniProt

P03956