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CD79b 抗体 (AA 29-229)

CD79B 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043398
发货至: 中国
  • 抗原 See all CD79b (CD79B) 抗体
    CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
    抗原表位
    • 25
    • 8
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-229
    适用
    • 113
    • 53
    • 19
    • 7
    • 7
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 56
    • 55
    • 15
    • 9
    • 4
    • 2
    • 1
    克隆类型
    • 87
    • 49
    • 1
    多克隆
    标记
    • 75
    • 16
    • 15
    • 10
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD79b antibody is un-conjugated
    应用范围
    • 80
    • 69
    • 40
    • 38
    • 37
    • 12
    • 11
    • 11
    • 11
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    原理
    Anti-CD79b Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-CD79b Antibody Picoband® (ABIN3043398). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human CD79b recombinant protein (Position: A29-E229). Human CD79b shares 70% amino acid (aa) sequence identity with mouse CD79b.
    亚型
    IgG
    Top Product
    Discover our top product CD79B Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL, Human
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    1. "Entrez Gene: CD79B CD79b molecule, immunoglobulin-associated beta" 2. Dobbs, A. K., Yang, T., Farmer, D., Kager, L., Parolini, O., Conley, M. E. Cutting edge: a hypomorphic mutation in Ig-beta (CD79b) in a patient with immunodeficiency and a leaky defect in B cell development. J. Immun. 179: 2055-2059, 2007. 3. Wood, W. J., Jr., Thompson, A. A., Korenberg, J., Chen, X., May, W., Wall, R., Denny, C. T. Isolation and chromosomal mapping of the human immunoglobulin-associated B29 gene (IGB). Genomics 16: 187-192, 1993.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
    别名
    CD79B (CD79B 产品)
    背景

    Synonyms: B-cell antigen receptor complex-associated protein beta chain,B-cell-specific glycoprotein B29,Ig-beta,Immunoglobulin-associated B29 protein,CD79b,CD79B,B29, IGB,

    Tissue Specificity: B-cells.

    Background: CD79b molecule, immunoglobulin-associated beta, also known as CD79B (Cluster of Differentiation 79B), is a human gene. By fluorescence in situ hybridization, It is mapped to 17q23.3. The CD79B protein together with the related CD79A protein, forms a dimer associated with membrane bound immunoglobulin in B-cells, thus forming the B-cell antigen receptor (BCR) which is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). CD79b also can enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.

    Sequence Similarities: Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    分子量
    35 kDa
    基因ID
    974
    UniProt
    P40259
    途径
    BCR Signaling
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