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CD22 抗体 (C-Term)

Name: CD22 抗体 (C-Term)
SKU: ABIN3043390
Availability: OutOfStock

CD22 适用: 人, 小鼠, 大鼠 FACS, WB, IHC 宿主: 兔 Polyclonal unconjugated

Flow Cytometry analysis of Raji cells using anti-CD22 antibody . (CD22 抗体 (C-Term))

FACS

Western Blotting (WB) image for anti-CD22 Molecule (CD22) (AA 696-724), (C-Term) antibody (ABIN3043390) (CD22 抗体 (C-Term))

Anti- CD22 Picoband antibody, IHC(P) IHC(P): Human Tonsil Tissue (CD22 抗体 (C-Term))

IHC

3 images

(2 references)

产品编号 ABIN3043390

发货至: 中国

Datasheet as PDF

抗原 See all CD22 抗体

CD22 (CD22 Molecule (CD22))
抗原表位
16

11

7

4

4

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 696-724, C-Term
适用
120

53

24

5

2

2

1
人, 小鼠, 大鼠
宿主
74

56

16

3
兔
Compatible Secondaries
克隆类型
101

46

1
多克隆
标记
81

12

9

5

4

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This CD22 antibody is un-conjugated
应用范围
90

62

43

34

33

17

11

11

9

8

5

4

3

3

2

2

2

2

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC)

原理

Anti-CD22 Antibody Picoband®

序列

LAILILAICG LKLQRRWKRT QSQQGLQEN

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-CD22 Antibody Picoband® (ABIN3043390). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human CD22, different from the related mouse sequence by ten amino acids.

亚型

IgG

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CD22 适用: 人 FACS, WB, ELISA, IF, IP 宿主: 兔 Monoclonal DM13 unconjugated

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CD22 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-022R unconjugated Recombinant Antibody

anti-CD22 Molecule (CD22) (AA 708-847) antibody
CD22 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-CD22 Molecule (CD22) antibody (Biotin)
GMP Grade CD22 适用: 人 FACS 宿主: 小鼠 Monoclonal MYG13 Biotin

anti-CD22 Molecule (CD22) antibody (PE)
GMP Grade CD22 适用: 人 FACS 宿主: 小鼠 Monoclonal MYG13 PE

应用备注

Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry, 1-3 μg/1x10⁶cells, Human
1. John, B., Herrin, B. R., Raman, C., Wang, Y., Bobbitt, K. R., Brody, B. A., Justement, L. B. The B cell coreceptor CD22 associates with AP50, a clathrin-coated pit adapter protein, via tyrosine-dependent interaction. J. Immun. 170: 3534-3543, 2003. 2. O'Keefe, T. L., Williams, G. T., Davies, S. L., Neuberger, M. S. Hyperresponsive B cells in CD22-deficient mice. Science 274: 798-801, 1996. 3. Wilson, G. L., Najfeld, V., Kozlow, E., Menniger, J., Ward, D., Kehrl, J. H. Genomic structure and chromosomal mapping of the human CD22 gene. J. Immun. 150: 5013-5024, 1993.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Huang, Zhu, Zhang, Zhu, Liu, Zhu, Wang, Li, Yang, Dong, Liu, Chen, Zhang, Yang, Deng, Fan, Wang, Liu, Ma, Fu, Wu: "S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, (2013) (PubMed).

Yu, Li, Li, Zang, Liu: "TRAIL and DR5 promote thyroid follicular cell apoptosis in iodine excess-induced experimental autoimmune thyroiditis in NOD mice." in: Biological trace element research, Vol. 143, Issue 2, pp. 1064-76, (2011) (PubMed).
抗原

CD22 (CD22 Molecule (CD22))

别名

CD22 (CD22 产品)

背景

Synonyms: B-cell receptor CD22,B-lymphocyte cell adhesion molecule,BL-CAM,Sialic acid-binding Ig-like lectin 2,Siglec-2,T-cell surface antigen Leu-14,CD22,CD22,SIGLEC2,
Tissue Specificity: B-lymphocytes.
Background: CD22 is a surface glycoprotein of B lymphocytes that is rapidly phosphorylated on cytoplasmic tyrosines after antigen receptor cross-linking. It is a negative regulator of antigen receptor signaling whose onset of expression at the mature B cell stage may serve to raise the antigen concentration threshold required for B cell triggering. The human CD22 gene is expressed specifically in B lymphocytes and likely has an important function in cell-cell interactions. The B cell coreceptor CD22 plays an important role in regulating signal transduction via the B cell Ag receptor. And CD22 is located within the band region q13.1 of chromosome 19.

分子量

140 kDa

基因ID

933

UniProt

P20273