MAD1L1 抗体 (AA 362-632)
Quick Overview for MAD1L1 抗体 (AA 362-632) (ABIN3043387)
抗原
See all MAD1L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 362-632
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原理
- Anti-MAD1/MAD1L1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-MAD1/MAD1L1 Antibody Picoband® (ABIN3043387). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MAD1 recombinant protein (Position: L362-A632). Human MAD1 shares 81% amino acid (aa) sequence identity with mouse MAD1.
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亚型
- IgG
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anti-MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1) (AA 360-700) antibody
MAD1L1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1) (N-Term) antibodyMAD1L1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1) antibodyMAD1L1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1) (AA 394-443) antibodyMAD1L1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1) antibodyMAD1L1 适用: 人 WB, IF, IP 宿主: 小鼠 Monoclonal 9B10 unconjugated
anti-MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1) antibodyMAD1L1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 9B10 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry, 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. "Entrez Gene: MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)" 2. Jin, D.-Y., Kozak, C. A., Pangilinan, F., Spencer, F., Green, E. D., Jeang, K.-T. Mitotic checkpoint locus MAD1L1 maps to human chromosome 7p22 and mouse chromosome 5. Genomics 55: 363-364, 1999. 3. Jin, D.-Y., Spencer, F., Jeang, K.-T. Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1. Cell 93: 81-91, 1998. 4. Tsukasaki, K., Miller, C. W., Greenspun, E., Eshaghian, S., Kawabata, H., Fujimoto, T., Tomonaga, M., Sawyers, C., Said, J. W., Koeffler, H. P. Mutations in the mitotic check point gene, MAD1L1, in human cancers. Oncogene 20: 3301-3305, 2001. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))
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别名
- MAD1L1
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背景
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Synonyms: Mitotic spindle assembly checkpoint protein MAD1,Mitotic arrest deficient 1-like protein 1,MAD1-like protein 1,Mitotic checkpoint MAD1 protein homolog,HsMAD1,hMAD1,Tax-binding protein 181,MAD1L1,MAD1, TXBP181,
Tissue Specificity: Expressed weakly at G0/G1 and highly at late S and G2/M phase.
Background: Mitotic spindle assembly checkpoint protein MAD1 is a protein that in humans is encoded by the MAD1L1 gene. It is mapped to 7p22.3. MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 can function as a homodimer. It localizes to the centrosome during metaphase and to the spindle midzone and the midbody during anaphase and telophase. MAD1L1 may also play a role in cell cycle control and tumor suppression.
Sequence Similarities: Belongs to the MAD1 family.
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分子量
- 83 kDa
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基因ID
- 8379
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UniProt
- Q9Y6D9
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途径
- M Phase
抗原
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