PLD1 抗体 (AA 1-330)
Quick Overview for PLD1 抗体 (AA 1-330) (ABIN3043383)
抗原
See all PLD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-330
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原理
- Anti-Phospholipase D1/PLD1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Phospholipase D1/PLD1 Antibody Picoband® (ABIN3043383). Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PLD1 recombinant protein (Position: M1-H330). Human PLD1 shares 91.8% and 90.9% amino acid (aa) sequence identity with mouse and rat PLD1, respectively.
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亚型
- IgG
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anti-Phospholipase D1 (PLD1) (AA 965-1074) antibody
PLD1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 10H2 unconjugated
anti-Phospholipase D1 (PLD1) (AA 485-627) antibodyPLD1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase D1 (PLD1) (pThr147) antibodyPLD1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase D1 (PLD1) antibodyPLD1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase D1 (PLD1) (AA 527-576), (pSer561) antibodyPLD1 适用: 人, 小鼠, 大鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse
1. "Entrez Gene: PLD1 phospholipase D1, phosphatidylcholine-specific" 2. Colley, W. C., Altshuller, Y. M., Sue-Ling, C. K., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Branch, K. D., Tsirka, S. E., Bollag, R. J., Bollag, W. B., Frohman, M. A. Cloning and expression analysis of murine phospholipase D1. Biochem. J. 326: 745-753, 1997. 3. Park SH, Chun YH, Ryu SH, Suh PG, Kim H (February 1999). "Assignment of human PLD1 to human chromosome band 3q26 by fluorescence in situ hybridization". Cytogenet Cell Genet82 (3-4): 224. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PLD1 (Phospholipase D1 (PLD1))
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别名
- PLD1
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背景
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Synonyms: Phospholipase D1,PLD 1,hPLD1,3.1.4.4,Choline phosphatase 1,Phosphatidylcholine-hydrolyzing phospholipase D1,PLD1,
Tissue Specificity: Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine. .
Background: By somatic cell hybrid analysis, PLD1 is mapped to 3q26.31. This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. And PLD1 disrupted association of gamma-secretase protein components, independent of PLD1catalytic activity. What's more, PLD1 regulates intracellular trafficking of beta-amyloid, distinct from its effect on gamma-secretase activity.
Sequence Similarities: Belongs to the phospholipase D family.
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分子量
- 124 kDa
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基因ID
- 5337
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UniProt
- Q13393
抗原
-
