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PAX6 抗体 (Middle Region)

Name: PAX6 抗体 (Middle Region)
SKU: ABIN3043379
Availability: OutOfStock

This anti-PAX6 antibody is a 兔多克隆 antibody detecting PAX6 in WB 和 IHC. Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 1 publication.

Western Blotting (WB) image for anti-Paired Box 6 (PAX6) (AA 195-233), (Middle Region) antibody (ABIN3043379) (PAX6 抗体 (Middle Region))

Anti- PAX6 Picoband antibody, IHC(P) IHC(P): Rat Pancreas Tissue (PAX6 抗体 (Middle Region))

IHC

Anti- PAX6 Picoband antibody, IHC(P) IHC(P): Human Pancreatic Cancer Tissue (PAX6 抗体 (Middle Region))

IHC

Anti- PAX6 Picoband antibody, IHC(P) IHC(P): Mouse Pancreas Tissue (PAX6 抗体 (Middle Region))

IHC

4 images

(1 reference)

产品编号 ABIN3043379

发货至: 中国

Quick Overview for PAX6 抗体 (Middle Region) (ABIN3043379)

抗原

See all PAX6 抗体

PAX6 (Paired Box 6 (PAX6))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This PAX6 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product PAX6 Primary Antibody

抗原表位
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AA 195-233, Middle Region

原理

Anti-PAX6 Antibody Picoband®

序列

EDSDEAQMRL QLKRKLQRNR TSFTQEQIEA LEKEFERTH

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-PAX6 Antibody Picoband® (ABIN3043379). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human PAX6, identical to the related mouse and rat sequences.

亚型

IgG
anti-Paired Box 6 (PAX6) (AA 1-122) antibody
PAX6 适用: 人 ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 1F6G2 unconjugated

anti-Paired Box 6 (PAX6) (AA 51-150) antibody
PAX6 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Paired Box 6 (PAX6) (AA 183-210) antibody
PAX6 适用: 人 WB, IF, ELISA, FACS, IHC 宿主: 兔 Polyclonal unconjugated

anti-Paired Box 6 (PAX6) (AA 352-380) antibody
PAX6 适用: 人 WB, IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Paired Box 6 (PAX6) (AA 1-422) antibody
PAX6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Paired Box 6 (PAX6) (AA 352-380) antibody
PAX6 适用: 人, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15517 unconjugated

anti-Paired Box 6 (PAX6) (AA 1-300) antibody
PAX6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Paired Box 6 (PAX6) (AA 1-422) antibody
PAX6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Paired Box 6 (PAX6) antibody
PAX6 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-706M unconjugated

anti-Paired Box 6 (PAX6) (AA 1-300) antibody
PAX6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Gehring WJ, Ikeo K (September 1999). "Pax 6: mastering eye morphogenesis and eye evolution". Trends Genet. 15 (9): 371-7. 2. Jordan T, Hanson I, Zaletayev D, Hodgson S, Prosser J, Seawright A, Hastie N, van Heyningen V (August 1992). "The human PAX6 gene is mutated in two patients with aniridia". Nat. Genet. 1 (5): 328-32. 3. Walcher T, Xie Q, Sun J, Irmler M, Beckers J, 79ztürk T, Niessing D, Stoykova A, Cvekl A, Ninkovic J, Götz M (March 2013). "Functional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferation". Development 140 (5): 1123-36.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Liu, Novak, Pepin, Maschhoff, Worner, Chen, Zhang, Hu: "A congenital hydrocephalus-causing mutation in Trim71 induces stem cell defects via inhibiting Lsd1 mRNA translation." in: EMBO reports, Vol. 24, Issue 2, pp. e55843, (2023) (PubMed).
抗原

PAX6 (Paired Box 6 (PAX6))

别名

PAX6

背景

Synonyms: Paired box protein Pax-6,Aniridia type II protein,Oculorhombin,PAX6,AN2,
Tissue Specificity: Fetal eye, brain, spinal cord and olfactory epithelium. Isoform 5a is less abundant than the PAX6 shorter form.
Background: Paired box protein Pax-6, also known as aniridia type II protein (AN2) or oculorhombin, is a protein that in humans is encoded by the PAX6 gene. This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. In addition, this gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.

分子量

47 kDa

基因ID

5080

UniProt

P26367

途径

Peptide Hormone Metabolism, Carbohydrate Homeostasis