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OMG 抗体 (N-Term)

This anti-OMG antibody is a 兔 多克隆 antibody detecting OMG in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3043375
发货至: 中国

Quick Overview for OMG 抗体 (N-Term) (ABIN3043375)

抗原

See all OMG 抗体
OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This OMG antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 64-99, N-Term

    原理

    Anti-Oligodendrocyte myelin glycoprotein/OMG Antibody Picoband®

    序列

    YNHFTDLHNQ LTQYTNLRTL DISNNRLESL PAHLPR

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Oligodendrocyte myelin glycoprotein/OMG Antibody Picoband® (ABIN3043375). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human OMG, different from the related mouse sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. "Entrez Gene: OMG oligodendrocyte myelin glycoprotein". 2. Mikol DD, Alexakos MJ, Bayley CA, Lemons RS, Le Beau MM, Stefansson K (Mar 1991). "Structure and chromosomal localization of the gene for the oligodendrocyte-myelin glycoprotein". J Cell Biol 111 (6 Pt 1): 2673-9. 3. Viskochil D, Cawthon R, O'Connell P, Xu GF, Stevens J, Culver M, Carey J, White R (Mar 1991). "The gene encoding the oligodendrocyte-myelin glycoprotein is embedded within the neurofibromatosis type 1 gene". Mol Cell Biol 11 (2): 906-12.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

    别名

    OMG

    背景

    Synonyms: Oligodendrocyte-myelin glycoprotein,OMG,OMGP,

    Tissue Specificity: Oligodendrocytes and myelin of the central nervous system.

    Background: Oligodendrocyte-myelin glycoprotein is a protein that in humans is encoded by the OMG gene. This gene is mapped to 17q11-q12. OMG, like neurofibromin (NF1), has growth suppressive effects and downregulates mitogenic signaling pathways closely related to those influenced by neurofibromin. Overexpression of OMG alters mitogenic signaling in fibroblasts. Cells overexpressing OMG grow more slowly in serum compared to controls and show a partial G1 block upon cell cycle analysis.

    分子量

    50 kDa

    基因ID

    4974

    UniProt

    P23515

    途径

    Neurotrophin Signaling Pathway, Regulation of Cell Size
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