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SMC3 抗体 (C-Term)

This anti-SMC3 antibody is a 兔 多克隆 antibody detecting SMC3 in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3043343
发货至: 中国

Quick Overview for SMC3 抗体 (C-Term) (ABIN3043343)

抗原

See all SMC3 抗体
SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This SMC3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1178-1216, C-Term

    原理

    Anti-SMC3 Antibody Picoband®

    序列

    ELLESADKFY GVKFRNKVSH IDVITAEMAK DFVEDDTTH

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SMC3 Antibody Picoband® (ABIN3043343). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human SMC3, identical to the related mouse sequence.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. "Entrez Gene: SMC3 structural maintenance of chromosomes 3". 2. Ghiselli G, Coffee N, Munnery CE, Koratkar R, Siracusa LD (2003). "The cohesin SMC3 is a target the for beta-catenin/TCF4 transactivation pathway".J. Biol. Chem. 278 (22): 20259-67. 3. Patel CA, Ghiselli G (2005). "Hinderin, a five-domains protein including coiled-coil motifs that binds to SMC3". BMC Cell Biol. 6 (1): 3.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

    别名

    SMC3

    背景

    Synonyms: Structural maintenance of chromosomes protein 3,SMC protein 3,SMC-3,Basement membrane-associated chondroitin proteoglycan,Bamacan,Chondroitin sulfate proteoglycan 6,Chromosome-associated polypeptide,hCAP,SMC3,BAM, BMH, CSPG6, SMC3L1,

    Tissue Specificity: Predominantly expressed in the brain.

    Background: Structural maintenance of chromosomes 3, also known as SMC3, is a human gene. This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein.

    分子量

    140 kDa

    基因ID

    9126

    途径

    Stem Cell Maintenance
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