SIRT7 抗体 (AA 8-350)
Quick Overview for SIRT7 抗体 (AA 8-350) (ABIN3043336)
抗原
See all SIRT7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 8-350
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原理
- Anti-SIRT7 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SIRT7 Antibody Picoband® (ABIN3043336). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SIRT7 recombinant protein (Position: R8-G350). Human SIRT7 shares 96% and 95% amino acid (aa) sequence identity with mouse and rat SIRT7, respectively.
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亚型
- IgG
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anti-Sirtuin 7 (SIRT7) (AA 1-400) antibody
SIRT7 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 7 (SIRT7) (AA 1-105) antibodySIRT7 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 1E2G10 unconjugated
anti-Sirtuin 7 (SIRT7) (AA 1-400) antibodySIRT7 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Sirtuin 7 (SIRT7) (AA 201-400) antibodySIRT7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 7 (SIRT7) (AA 1-105) antibodySIRT7 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1E2B2 unconjugated
anti-Sirtuin 7 (SIRT7) (AA 231-330) antibodySIRT7 适用: 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 7 (SIRT7) (AA 242-379) antibodySIRT7 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 7 (SIRT7) (AA 35-51), (AA 361-377) antibodySIRT7 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 7 (SIRT7) (AA 1-400) antibodySIRT7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 7 (SIRT7) (AA 135-274) antibodySIRT7 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Altered sirtuin expression is associated with node-positive breast cancer.Ashraf N, et al. Br J Cancer, 2006 Oct 23. 2. Molecular pathways: emerging roles of mammalian Sirtuin SIRT7 in cancer.Paredes S, et al. Clin Cancer Res, 2014 Apr 1. 3. Sirtuin 7 plays a role in ribosome biogenesis and protein synthesis.Tsai YC, et al. Mol Cell Proteomics, 2014 Jan. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SIRT7 (Sirtuin 7 (SIRT7))
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别名
- SIRT7
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背景
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Synonyms: NAD-dependent protein deacetylase sirtuin-7,3.5.1.-,Regulatory protein SIR2 homolog 7,SIR2-like protein 7,SIRT7,SIR2L7,
Background: SIRT7 is also known as SIR2L7. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
Sequence Similarities: Belongs to the sirtuin family. Class IV subfamily.
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分子量
- 40 kDa
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基因ID
- 51547
抗原
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