SERPINH1 抗体 (AA 247-418)
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Quick Overview for SERPINH1 抗体 (AA 247-418) (ABIN3043331)
抗原
See all SERPINH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 247-418
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原理
- Anti-Hsp47/SERPINH1 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human Hsp47 shares 97% amino acid (aa) sequence identity with both mouse,rat Hsp47.
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产品特性
- Anti-Hsp47/SERPINH1 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Hsp47 recombinant protein (Position: D247-L418). Human Hsp47 shares 97% amino acid (aa) sequence identity with both mouse and rat Hsp47.
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亚型
- IgG
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anti-Serpin Family H Member 1 (SERPINH1) (AA 1-418) antibody
SERPINH1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D2-1A6 unconjugated
anti-Serpin Family H Member 1 (SERPINH1) (Internal Region) antibodySERPINH1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Serpin Family H Member 1 (SERPINH1) antibodySERPINH1 适用: 人, 小鼠, 大鼠, Pig, 豚鼠, 兔, 绵羊 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal M16-10A1 unconjugated
anti-Serpin Family H Member 1 (SERPINH1) antibodySERPINH1 适用: 人, 小鼠, 大鼠, 犬, Pig, 小鸡, Cow, 豚鼠, 兔, 绵羊, Hamster, 猴 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal M16-10A1 unconjugated
anti-Serpin Family H Member 1 (SERPINH1) (Internal Region) antibodySERPINH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Serpin Family H Member 1 (SERPINH1) (AA 1-418) antibodySERPINH1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Serpin Family H Member 1 (SERPINH1) antibodySERPINH1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 1C4-1A6 unconjugated
anti-Serpin Family H Member 1 (SERPINH1) antibody (Atto 488)SERPINH1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 1C4-1A6 Atto 488
anti-Serpin Family H Member 1 (SERPINH1) antibody (Atto 390)SERPINH1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 1C4-1A6 Atto 390
anti-Serpin Family H Member 1 (SERPINH1) antibody (Atto 594)SERPINH1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 1C4-1A6 Atto 594
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应用备注
- Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, HumanWestern blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- SERPINH1 (Serpin Family H Member 1 (SERPINH1))
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别名
- SERPINH1
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背景
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Background: Heat shock protein 47, also known as SERPINH1 or HSP47, is a serpin which serves as a human chaperone protein for collagen. This protein is a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. The protein localizes to the endoplasmic reticulum lumen and binds collagen, thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. It has been found that HSP47 monitors the integrity of the triple helix of type I procollagen at the ER/cis-Golgi boundary and, when absent, the rate of transit from the ER to the Golgi is increased and the helical structure is compromised.
Gene Full Name: serpin family H member 1
Sequence Similarities: Belongs to the serpin family.
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分子量
- 46 kDa
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基因ID
- 871
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UniProt
- P50454
抗原
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