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SCARB1 抗体 (C-Term)

The 兔 多克隆 anti-SCARB1 antibody is suitable to detect SCARB1 in samples from 大鼠 和 小鼠. It has been validated for WB 和 IHC.
产品编号 ABIN3043322
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SCARB1 抗体 (C-Term) (ABIN3043322)

抗原

See all SCARB1 抗体
SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

适用

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  • 2
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  • 1
大鼠, 小鼠

宿主

  • 57
  • 11
  • 2

克隆类型

  • 37
  • 33
多克隆

标记

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  • 1
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This SCARB1 antibody is un-conjugated

应用范围

  • 44
  • 26
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  • 16
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  • 8
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  • 5
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  • 2
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 7
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    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    C-Term

    原理

    Anti-Scavenging Receptor SR-BI/SCARB1 Antibody

    序列

    KKGSQDKEAI QAYSESLMSP AAKGTVLQEA KL

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related rat sequence by one amino acid.

    产品特性

    Anti-Scavenging Receptor SR-BI/SCARB1 Antibody. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse SCARB1, different from the related rat sequence by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Rat

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

    别名

    Scarb1

    背景

    Background: Scavenger receptor class B member 1 (SRB1), also known as SR-BI, is a protein that in humans is encoded by the SCARB1 gene. SR-BI functions as a receptor for high-density lipoprotein. Scavenger receptor class B, type I (SR-BI) is an integral membrane protein found in numerous cell types/tissues, including the liver and adrenal. It is best known for its role in facilitating the uptake of cholesteryl esters from high-density lipoproteins in the liver. This process drives the movement of cholesterol from peripheral tissues towards the liver for excretion. This movement of cholesterol is known as reverse cholesterol transport and is a protective mechanism against the development of atherosclerosis, which is the principal cause of heart disease and stroke. SR-BI has also been identified in the livers of non-mammalian species (turtle, goldfish, shark, chicken, frog, and skate), suggesting it emerged early in vertebrate evolutionary history. The turtle also seems to upregulate SB-RI during egg development, indicating that cholesterol efflux may be at peak levels during developmental stages.

    Gene Full Name: scavenger receptor class B, member 1

    分子量

    57 kDa

    基因ID

    20778

    UniProt

    Q61009

    途径

    Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome
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