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TJP1 抗体 (AA 1178-1527)

Name: TJP1 抗体 (AA 1178-1527)
SKU: ABIN3043312
Availability: OutOfStock

TJP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated

Anti- TJP1 antibody, Western blotting All lanes: Anti TJP1 at 0. (TJP1 抗体 (AA 1178-1527))

Anti- TJP1 antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue (TJP1 抗体 (AA 1178-1527))

IHC

Western blot analysis of TJP1 using anti- TJP1 antibody . (TJP1 抗体 (AA 1178-1527))

Western Blotting (WB) image for anti-Tight Junction Protein 1 (TJP1) (AA 1178-1527) antibody (ABIN3043312) (TJP1 抗体 (AA 1178-1527))

4 images

(4 references)

产品编号 ABIN3043312

发货至: 中国

Datasheet as PDF

抗原 See all TJP1 抗体

TJP1 (Tight Junction Protein 1 (TJP1))
抗原表位
15

6

4

4

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1178-1527
适用
56

34

33

18

17

8

4

4

3

2

1

1

1

1

1

1

1

1
人, 小鼠, 大鼠
宿主
53

3

1

1

1
兔
Compatible Secondaries
克隆类型
54

5
多克隆
标记
36

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This TJP1 antibody is un-conjugated
应用范围
48

21

17

17

14

13

12

10

10

8

8

2

2

2

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

原理

Anti-ZO1 tight junction protein/TJP1 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-ZO1 tight junction protein/TJP1 Antibody Picoband® (ABIN3043312). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human TJP1 recombinant protein (Position: H1178-F1527). Human TJP1 shares 82% amino acid (aa) sequence identity with mouse TJP1.

亚型

IgG

Top Product

Discover our top product TJP1 Primary Antibody
anti-Tight Junction Protein 1 (TJP1) (AA 1551-1702) antibody
TJP1 适用: 人, 小鼠, 大鼠, Pig, Cow WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Tight Junction Protein 1 (TJP1) (C-Term) antibody
TJP1 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬, 豚鼠, 兔, 马, 猴, 小鸡, Avian, Cat, 驴, 山羊, Hamster, 绵羊 WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated

anti-Tight Junction Protein 1 (TJP1) (N-Term) antibody
KO Validated TJP1 适用: 人 WB, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tight Junction Protein 1 (TJP1) (Internal Region) antibody
Verified TJP1 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Tight Junction Protein 1 (TJP1) antibody
TJP1 适用: 人 WB, IHC, ELISA, IF, FACS, FM, MA 宿主: 兔 Polyclonal unconjugated

anti-Tight Junction Protein 1 (TJP1) antibody
TJP1 适用: 人 WB, IHC, ELISA, IF, FACS, FM, MA 宿主: 兔 Polyclonal unconjugated

anti-Tight Junction Protein 1 (TJP1) antibody
TJP1 适用: 人, 小鼠, 大鼠, Pig WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tight Junction Protein 1 (TJP1) antibody
TJP1 适用: 小鼠 WB, IHC, IP 宿主: 大鼠 Monoclonal unconjugated

anti-Tight Junction Protein 1 (TJP1) (AA 1-190) antibody
TJP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tight Junction Protein 1 (TJP1) (AA 23-502) antibody
TJP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human1. Mohandas TK, Chen XN, Rowe LB, Birkenmeier EH, Fanning AS, Anderson JM, Korenberg JR (February 1997). "Localization of the tight junction protein gene TJP1 to human chromosome 15q13, distal to the Prader-Willi/Angelman region, and to mouse chromosome 7". Genomics 30 (3): 594-7. 2. Willott, E., Balda, M. S., Fanning, A. S., Jameson, B., Van Itallie, C., Anderson, J. M. The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions. Proc. Nat. Acad. Sci. 90: 7834-7838, 1993.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Liu, Mei, Xu, Yu, Shi, Zhang, Wang, Zhang, Gao, Zhang, He: "Dual Receptor Recognizing Cell Penetrating Peptide for Selective Targeting, Efficient Intratumoral Diffusion and Synthesized Anti-Glioma Therapy." in: Theranostics, Vol. 6, Issue 2, pp. 177-91, (2017) (PubMed).

Subramani, Ponnalagu, Krishna, Jeyabalan, Chevour, Sharma, Jayadev, Shetty, Begum, Archunan, Das: "Resveratrol reverses the adverse effects of bevacizumab on cultured ARPE-19 cells." in: Scientific reports, Vol. 7, Issue 1, pp. 12242, (2017) (PubMed).

Lv, Phuong, Jin, Li, Xu: "Protection by simvastatin on hyperglycemia-induced endothelial dysfunction through inhibiting NLRP3 inflammasomes." in: Oncotarget, Vol. 8, Issue 53, pp. 91291-91305, (2017) (PubMed).

Wen, Huang, Zhang, Zhang, Chen, Gu, Hao: "Resveratrol attenuates diabetic nephropathy via modulating angiogenesis." in: PLoS ONE, Vol. 8, Issue 12, pp. e82336, (2013) (PubMed).
抗原

TJP1 (Tight Junction Protein 1 (TJP1))

别名

TJP1 (TJP1 产品)

背景

Synonyms: Tight junction protein ZO-1,Tight junction protein 1,Zona occludens protein 1,Zonula occludens protein 1,TJP1,ZO1,
Tissue Specificity: The alpha-containing isoform is found in most epithelial cell junctions. The short isoform is found both in endothelial cells and the highly specialized epithelial junctions of renal glomeruli and Sertoli cells of the seminiferous tubules.
Background: Tight junction protein ZO-1 is a protein that in humans is encoded by the TJP1 gene. It is mapped to 15q13.1. This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. It has been found that injected CagA associates with the epithelial tight-junction scaffolding protein TJP1 and the transmembrane protein junctional adhesion molecule, causing an ectopic assembly of tight junction components at sites of bacterial attachment, and altering the composition and function of the apical-junctional complex.
Sequence Similarities: Belongs to the MAGUK family.

分子量

220 kDa

基因ID

7082

UniProt

Q07157

途径

Carbohydrate Homeostasis, Cell-Cell Junction Organization