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Synaptophysin 抗体 (N-Term)

SYP 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043307
发货至: 中国
  • 抗原 See all Synaptophysin (SYP) 抗体
    Synaptophysin (SYP)
    抗原表位
    • 13
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-26, N-Term
    适用
    • 74
    • 54
    • 53
    • 10
    • 10
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 52
    • 34
    • 3
    • 1
    克隆类型
    • 50
    • 40
    多克隆
    标记
    • 68
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Synaptophysin antibody is un-conjugated
    应用范围
    • 68
    • 42
    • 28
    • 21
    • 20
    • 15
    • 15
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Synaptophysin(SYP) detection. Tested with WB in Human,Mouse,Rat.
    序列
    MLLLADMDVV NQLVAGGQFR VVKEPL
    交叉反应 (详细)
    Predicted Cross Reactivity: human
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Synaptophysin(SYP) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: synaptophysin
    Protein Name: Synaptophysin
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human Synaptophysin(1-26aa MLLLADMDVVNQLVAGGQFRVVKEPL), identical to the related mouse and rat sequences.
    亚型
    IgG
    Top Product
    Discover our top product SYP Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human , The detection limit for Synaptophysin is approximately 0.1 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Chen, Wei, Nie, Lin, Tian, Liu, Yu, Cheng, Yan, Wang, Liu, Deng, Lai, Zhou, Zhang, Lin, Chen: "?-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in asenescence-accelerated prone 8 mice." in: Brain research, Vol. 1552, pp. 41-54, (2014) (PubMed).

    Liu, Liang, Liu, Zou, Li, Wang, An: "Downregulation of caveolin-1 contributes to the synaptic plasticity deficit in the hippocampus of aged rats." in: Neural regeneration research, Vol. 8, Issue 29, pp. 2725-33, (2014) (PubMed).

    Li, Xin, Wang, Wu, Jin, Ma, Nie, Xiao, Hu, Jin: "Pentamethylquercetin protects against diabetes-related cognitive deficits in diabetic Goto-Kakizaki rats." in: Journal of Alzheimer's disease : JAD, Vol. 34, Issue 3, pp. 755-67, (2013) (PubMed).

  • 抗原
    Synaptophysin (SYP)
    别名
    SYP (SYP 产品)
    别名
    syp-B antibody, xsypii antibody, MGC86267 antibody, MRXSYP antibody, A230093K24Rik antibody, AI848995 antibody, Syn antibody, p38 antibody, Syp1 antibody, mrxsyp antibody, syp antibody, xsypi antibody, synaptophysin S homeolog antibody, synaptophysin antibody, synaptophysin L homeolog antibody, synaptophysin a antibody, syp.S antibody, SYP antibody, syp antibody, Syp antibody, syp.L antibody, sypa antibody
    背景
    SYP(Synaptophysin) is located on the short arm of X chromosome (Xp11.23-p11.22). The protein is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38 kDa. It is present inneuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for neuroendocrine tumors, and its ubiquity at the synapse has led to the use of synaptophysin immunostaining for quantification of synapses. Also, the protein binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR).

    Synonyms: Major synaptic vesicle protein P38 antibody|MRXSYP antibody|Syn p38 antibody|Synaptophysin antibody|SYP antibody|SYPH antibody|SYPH_HUMAN antibody|SypI antibody
    基因ID
    6855
    UniProt
    P08247
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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