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Synaptophysin 抗体 (N-Term)

Name: Synaptophysin 抗体 (N-Term)
SKU: ABIN3043307
Availability: OutOfStock

This anti-Synaptophysin antibody is a 兔多克隆 antibody detecting Synaptophysin in WB. Suitable for 人, 大鼠和小鼠. This Primary Antibody has been cited in 3+ publications.

Anti- Synaptophysin Picoband antibody, Western blottingAll lanes: Anti Synaptophysin at 0. (Synaptophysin 抗体 (N-Term))

1 image

(3 references)

产品编号 ABIN3043307

发货至: 中国

Quick Overview for Synaptophysin 抗体 (N-Term) (ABIN3043307)

抗原

See all Synaptophysin (SYP) 抗体

Synaptophysin (SYP)

适用

人, 大鼠, 小鼠

宿主

兔

克隆类型

多克隆

标记

This Synaptophysin antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product SYP Primary Antibody

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AA 1-26, N-Term

原理

Anti-Synaptophysin/SYP Antibody Picoband®

序列

MLLLADMDVV NQLVAGGQFR VVKEPL

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Synaptophysin/SYP Antibody Picoband® (ABIN3043307). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human Synaptophysin, identical to the related mouse and rat sequences.

亚型

IgG
anti-Synaptophysin (SYP) (AA 150-250) antibody
SYP 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Synaptophysin (SYP) (C-Term) antibody
SYP 适用: 人 WB, IF, IHC (p), ICC, IHC (fro), IHC (wm) 宿主: 兔 Polyclonal unconjugated

anti-Synaptophysin (SYP) (AA 225-253), (C-Term) antibody
SYP 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB32966 unconjugated

anti-Synaptophysin (SYP) (AA 225-253), (C-Term) antibody
SYP 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB32966 unconjugated

anti-Synaptophysin (SYP) (Internal Region) antibody
SYP 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Synaptophysin (SYP) antibody
SYP 适用: 人, 犬 WB, IF 宿主: 小鼠 Monoclonal 5H2 unconjugated

anti-Synaptophysin (SYP) (N-Term) antibody
SYP 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 山羊 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Synaptophysin (SYP) antibody
Microarray verified SYP 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB551901 unconjugated

anti-Synaptophysin (SYP) (AA 1-313) antibody
SYP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B3 unconjugated

anti-Synaptophysin (SYP) antibody
SYP 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3E2 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
1. Calhoun ME, Jucker M, Martin LJ, Thinakaran G, Price DL, Mouton PR (December 1996). "Comparative evaluation of synaptophysin-based methods for quantification of synapses". J. Neurocytol.25 (12): 821-8.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Chen, Wei, Nie, Lin, Tian, Liu, Yu, Cheng, Yan, Wang, Liu, Deng, Lai, Zhou, Zhang, Lin, Chen: "?-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in asenescence-accelerated prone 8 mice." in: Brain research, Vol. 1552, pp. 41-54, (2014) (PubMed).

Liu, Liang, Liu, Zou, Li, Wang, An: "Downregulation of caveolin-1 contributes to the synaptic plasticity deficit in the hippocampus of aged rats." in: Neural regeneration research, Vol. 8, Issue 29, pp. 2725-33, (2014) (PubMed).

Li, Xin, Wang, Wu, Jin, Ma, Nie, Xiao, Hu, Jin: "Pentamethylquercetin protects against diabetes-related cognitive deficits in diabetic Goto-Kakizaki rats." in: Journal of Alzheimer's disease : JAD, Vol. 34, Issue 3, pp. 755-67, (2013) (PubMed).
抗原

Synaptophysin (SYP)

别名

SYP

背景

Synonyms: Synaptophysin,Major synaptic vesicle protein p38,SYP,
Tissue Specificity: Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
Background: SYP (Synaptophysin) is located on the short arm of X chromosome (Xp11.23-p11.22). The protein is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38 kDa. It is present inneuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for neuroendocrine tumors, and its ubiquity at the synapse has led to the use of synaptophysin immunostaining for quantification of synapses. Also, the protein binds cholesterol and is thought to targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR).
Sequence Similarities: Belongs to the synaptophysin/synaptobrevin family.

分子量

38 kDa

基因ID

6855

UniProt

P08247

途径

Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity