STXBP2 抗体 (N-Term)
Quick Overview for STXBP2 抗体 (N-Term) (ABIN3043304)
抗原
See all STXBP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 184-215, N-Term
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原理
- Anti-STXBP2 Antibody Picoband®
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序列
- QEYPAIRYRK GPEDTAQLAH AVLAKLNAFK AD
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-STXBP2 Antibody Picoband® (ABIN3043304). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human STXBP2, different from the related mouse and rat sequences by one amino acid.
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亚型
- IgG
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anti-Syntaxin Binding Protein 2 (STXBP2) (pSer513) antibody
STXBP2 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 2 (STXBP2) antibodySTXBP2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 2 (STXBP2) (AA 1-280) antibodySTXBP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 2 (STXBP2) antibodySTXBP2 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 2 (STXBP2) (AA 58-70) antibodySTXBP2 适用: 人, 小鼠, 大鼠, Cow, 犬, Hamster, 马, 猴, Pig, 非洲爪蟾 WB, IHC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 2 (STXBP2) antibodySTXBP2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 2 (STXBP2) (AA 1-280) antibodySTXBP2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 2 (STXBP2) antibodySTXBP2 适用: 小鼠, 大鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. "Entrez Gene: STXBP2 syntaxin binding protein 2". 2. Cetica, V., Santoro, A., Gilmour, K. C., Sieni, E., Beutel, K., Pende, D., Marcenaro, S., Koch, F., Grieve, S., Wheeler, R., Zhao, F., zur Stadt, U., Griffiths, G. M., Arico, M. STXBP2 mutations in children with familial haemophagocytic lymphohistiocytosis type 5. J. Med. Genet. 47: 595-600, 2010. 3. Ziegler, S.F., Mortrud, M. T., Swartz, A. R., Baker, E., Sutherland, G. R., Burmeister, M., Mulligan, J. T. Molecular characterization of a nonneuronal human UNC18 homolog. Genomics 37: 19-23, 1996. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- STXBP2 (Syntaxin Binding Protein 2 (STXBP2))
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别名
- STXBP2
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背景
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Synonyms: Syntaxin-binding protein 2,Protein unc-18 homolog 2,Unc18-2,Protein unc-18 homolog B,Unc-18B,STXBP2,UNC18B,
Tissue Specificity: Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes.
Background: Syntaxin-binding protein 2, also known as UNC18B, is a protein that in humans is encoded by the STXBP2 gene. The STXBP2 gene is mapped to human chromosome 19p13.3-p13.2 and to the proximal arm of mouse chromosome 8. And this gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Additionally, UNC18B is expressed predominantly as a 2.4-kb message in placenta, lung, liver, kidney, and pancreas, as well as in peripheral blood lymphocytes. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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分子量
- 66 kDa
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基因ID
- 6813
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UniProt
- Q15833
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
抗原
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