SRSF1 抗体 (N-Term)
Quick Overview for SRSF1 抗体 (N-Term) (ABIN3043296)
抗原
See all SRSF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-33, N-Term
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原理
- Anti-SF2/SRSF1 Antibody Picoband®
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序列
- VIRGPAGNND CRIYVGNLPP DIRTKDIE
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SF2/SRSF1 Antibody Picoband® (ABIN3043296). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of Human SF2, identical to the related mouse sequence.
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亚型
- IgG
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anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) (pSer1) antibody
SRSF1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) (N-Term) antibodySRSF1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) (AA 158-186), (C-Term) antibodySRSF1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20788 unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) (C-Term) antibodySRSF1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 豚鼠, Cow, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) (AA 16-224) antibodySRSF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) (N-Term) antibodySRSF1 适用: 人, 小鼠, 大鼠 WB, IHC, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) antibodySRSF1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) (AA 11-38), (N-Term) antibodySRSF1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB22955 unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) antibodySRSF1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) (AA 1-248) antibodySRSF1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: SFRS1 splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor)". 2. Michlewski G, Sanford JR, Cáceres JF (April 2008). "The splicing factor SF2/ASF regulates translation initiation by enhancing phosphorylation of 4E-BP1". Mol. Cell 30 (2): 179-89. 3. Zuo P, Manley JL (December 1993)."Functional domains of the human splicing factor ASF/SF2". EMBO J. 12 (12): 4727-37. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SRSF1 (serine/arginine-Rich Splicing Factor 1 (SRSF1))
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别名
- SRSF1
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背景
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Synonyms: Serine/arginine-rich splicing factor 1,Alternative-splicing factor 1,ASF-1,Splicing factor, arginine/serine-rich 1,pre-mRNA-splicing factor SF2, P33 subunit,SRSF1,ASF, SF2, SF2P33, SFRS1,OK/SW-cl.3,
Tissue Specificity: Mainly expressed in the developing central nervous system.
Background: SF2, also known as Serine/arginine-rich splicing factor 1 (SRSF1), is a protein that in humans is encoded by the SFRS1 gene. This gene encodes a member of the arginine/serine-rich splicing factor protein family. There is a pseudogene of this gene on chromosome 13. The encoded protein can either activate or repress splicing, depending on its phosphorylation state and its interaction partners. Multiple transcript variants have been found for this gene. ASF/SF2 is necessary for all splicing reactions to occur, and influences splice site selection in a concentration-dependent manner, resulting in alternative splicing.
Sequence Similarities: Belongs to the splicing factor SR family.
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分子量
- 28 kDa
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基因ID
- 6426
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UniProt
- Q07955
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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