Lipocalin 2 抗体 (AA 21-198)
(2 references)-
- 抗原 See all Lipocalin 2 (LCN2) 抗体
- Lipocalin 2 (LCN2)
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抗原表位
- AA 21-198
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Lipocalin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 原理
- Anti-Lipocalin 2/LCN2 Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-Lipocalin 2/LCN2 Antibody Picoband® (ABIN3043292). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived < a href="https://www.bosterbio.com/human-lipocalin-2-ngal-picokine-trade-elisa-kit-ek0853-boster.html" style="color:#EA8D28">human Lipocalin 2 recombinant protein (Position: Q21-G198). Human Lipocalin 2 shares 62 % and 64.4 % amino acid (aa) sequence identity with mouse and rat Lipocalin 2, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product LCN2 Primary Antibody
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anti-Lipocalin 2 (LCN2) (AA 21-200) antibody
LCN2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-198) antibodyLCN2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-200) antibodyLCN2 适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 101-198) antibodyLCN2 适用: 人 ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-198) antibodyLCN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-198) antibodyLCN2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D14 unconjugated
anti-Lipocalin 2 (LCN2) (AA 1-198) antibodyLCN2 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) antibodyLCN2 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1A1B2 unconjugated
anti-Lipocalin 2 (LCN2) (AA 1-198) antibodyLCN2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (Internal Region) antibodyLCN2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
Western blot, 0.1-0.5 μg/mL, Human
1. Cowland JB, Borregaard N (October 1997). "Molecular characterization and pattern of tissue expression of the gene for neutrophil gelatinase-associated lipocalin from humans". Genomics 45 (1): 17-23. 2. Chan P, Simon-Chazottes D, Mattei MG, Guenet JL, Salier JP (September 1994). "Comparative mapping of lipocalin genes in human and mouse: the four genes for complement C8 gamma chain, prostaglandin-D-synthase, oncogene-24p3, and progestagen-associated endometrial protein map to HSA9 and MMU2". Genomics 23 (1): 145-50. 3. Flo TH, Smith KD, Sato S, Rodriguez DJ, Holmes MA, Strong RK, Akira S, Aderem A (December 2004). "Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron". Nature 432 (7019): 917-21. 4. Kjeldsen L, Johnsen AH, Sengel111v H, Borregaard N (May 1993). "Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase". J. Biol. Chem. 268 (14): 10425-32. 5. Nelson AM, Zhao W, Gilliland KL, Zaenglein AL, Liu W, Thiboutot DM (April 2008). 6. Schmidt-Ott KM, Mori K, Li JY, Kalandadze A, Cohen DJ, Devarajan P, Barasch J (February 2007). "Dual action of neutrophil gelatinase-associated lipocalin". J. Am. Soc. Nephrol. 18 (2): 407-13. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Late intervention with the small molecule BB3 mitigates postischemic kidney injury." in: American journal of physiology. Renal physiology, Vol. 311, Issue 2, pp. F352-61, (2017) (PubMed).
: "Expression of neutrophil gelatinase-associated lipocalin in low osmolar contrast-induced nephropathy in rats and the effect of N-acetylcysteine." in: Experimental and therapeutic medicine, Vol. 12, Issue 5, pp. 3175-3180, (2016) (PubMed).
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: "Late intervention with the small molecule BB3 mitigates postischemic kidney injury." in: American journal of physiology. Renal physiology, Vol. 311, Issue 2, pp. F352-61, (2017) (PubMed).
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- 抗原
- Lipocalin 2 (LCN2)
- 别名
- LCN2 (LCN2 产品)
- 背景
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Synonyms: Neutrophil gelatinase-associated lipocalin,NGAL,25 kDa alpha-2-microglobulin-related subunit of MMP-9,Lipocalin-2,Oncogene 24p3,Siderocalin LCN2,p25,LCN2,HNL, NGAL,
Tissue Specificity: Expressed in bone marrow and in tissues that are prone to exposure to microorganism. High expression is found in bone marrow as well as in uterus, prostate, salivary gland, stomach, appendix, colon, trachea and lung. Not found in the small intestine or peripheral blood leukocytes. .
Background: Europhile gelatinase-associated lipocalin (NGAL) is a protein that in humans is encoded by the LCN2 gene. The binding of lipocalin-2 to bacterial siderophores is important in the innate immune response to bacterial infection. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor.
Sequence Similarities: Belongs to the calycin superfamily. Lipocalin family.
- 分子量
- 22 kDa
- 基因ID
- 3934
- UniProt
- P80188
- 途径
- Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis
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