KIF2C 抗体 (AA 531-725)
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- 抗原 See all KIF2C 抗体
- KIF2C (Kinesin Family Member 2C (KIF2C))
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抗原表位
- AA 531-725
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KIF2C antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- Anti-MCAK/KIF2C Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-MCAK/KIF2C Antibody Picoband® (ABIN3043278). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human MCAK recombinant protein (Position: G531-Q725). Human MCAK shares 87% amino acid (aa) sequence identity with both mouse and rat MCAK.
- 亚型
- IgG
- Top Product
- Discover our top product KIF2C Primary Antibody
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anti-Kinesin Family Member 2C (KIF2C) (AA 1-100) antibody
KIF2C 适用: 人 WB, IF, ELISA, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Kinesin Family Member 2C (KIF2C) antibodyKIF2C 适用: 人, 小鼠, 大鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 2C (KIF2C) (C-Term) antibodyKIF2C 适用: 人, 小鼠, 大鼠 WB, IF, ELISA, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 2C (KIF2C) antibodyKIF2C 适用: 人 WB, ICC, FACS, DB 宿主: 小鼠 Monoclonal 2488C3a unconjugated
anti-Kinesin Family Member 2C (KIF2C) (AA 1-190) antibodyKIF2C 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 2C (KIF2C) antibodyKIF2C 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 2C (KIF2C) (AA 1-725) antibodyKIF2C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 2C (KIF2C) antibodyKIF2C 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 2C (KIF2C) (AA 9-287) antibodyKIF2C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 2C (KIF2C) (AA 50-100) antibodyKIF2C 适用: 人, 兔, 马 IF, IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Manning, A. L., Ganem, N. J., Bakhoum, S. F., Wagenbach, M., Wordeman, L., Compton, D. A. The kinesin-13 proteins, Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells. Molec. Biol. Cell 18: 2970-2979, 2007. 2. Kim IG, Jun DY, Sohn U, Kim YH (Feb 1998). "Cloning and expression of human mitotic centromere-associated kinesin gene". Biochim Biophys Acta 1359 (3): 181-6. 3. "Entrez Gene: KIF2C kinesin family member 2C" - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- 抗原
- KIF2C (Kinesin Family Member 2C (KIF2C))
- 别名
- KIF2C (KIF2C 产品)
- 背景
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Synonyms: Kinesin-like protein KIF2C,Kinesin-like protein 6,Mitotic centromere-associated kinesin,MCAK,KIF2C,KNSL6,
Tissue Specificity: Expressed at high levels in thymus and testis, at low levels in small intestine, the mucosal lining of colon, and placenta, and at very low levels in spleen and ovary, expression is not detected in prostate, peripheral blood Leukocytes, heart, brain, lung, liver, skeletal muscle, kidney or pancreas. Isoform 2 is testis-specific. .
Background: Kinesin-like protein KIF2C is a protein that in humans is encoded by the KIF2C gene. It is mapped to 1p34.1. The protein encoded by this gene is a member of kinesin-like protein family. Most proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation. KIF2C uses microtubule depolymerizing activity to correct improper microtubule attachments at kinetochores.
Sequence Similarities: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily.
- 分子量
- 81 kDa
- 基因ID
- 11004
- UniProt
- Q99661
- 途径
- Microtubule Dynamics
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