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DGAT1 抗体 (Middle Region)

This 兔 多克隆 anti-DGAT1 antibody specifically detects DGAT1 in WB. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN3043266
发货至: 中国
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Room 801-803
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Quick Overview for DGAT1 抗体 (Middle Region) (ABIN3043266)

抗原

See all DGAT1 抗体
DGAT1 (Diacylglycerol O-Acyltransferase 1 (DGAT1))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This DGAT1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 280-318, Middle Region

    原理

    Anti-DGAT1 Antibody

    序列

    RRILEMLFFT QLQVGLIQQW MVPTIQNSMK PFKDMDYSR

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-DGAT1 Antibody (ABIN3043266). Tested in WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human DGAT1, different from the related mouse and rat sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    DGAT1 (Diacylglycerol O-Acyltransferase 1 (DGAT1))

    别名

    DGAT1

    背景

    Synonyms: Diacylglycerol O-acyltransferase 1,2.3.1.20 ,ACAT-related gene product 1,Acyl-CoA retinol O-fatty-acyltransferase,ARAT,Retinol O-fatty-acyltransferase,2.3.1.76 ,Diglyceride acyltransferase,DGAT1,AGRP1, DGAT,

    Tissue Specificity: Widely expressed.

    Background: Acyl-CoA: diacylglycerol acyltransferase (DGAT) is a microsomal enzyme that plays a central role in the metabolism of cellular diacylglycerol lipids and catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT had been considered necessary for adipose tissue formation and essential for survival. There are two isozymes of DGAT encoded by the genes DGAT1 and DGAT2. DGAT1 is a host factor for HCV infection that binds core protein, localizes it to DGAT1-generated lipid droplets, and recruits viral RNA replication complexes for viral assembly. DGAT2-generated lipid droplets formed normally in cells treated with the DGAT1 inhibitor, suggesting that DGAT1 inhibitors may be useful as antiviral therapeutics.

    分子量

    60 kDa

    基因ID

    8694

    UniProt

    O75907

    途径

    Hormone Transport
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