ITGB1 抗体 (AA 527-728)
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北京 101111
Quick Overview for ITGB1 抗体 (AA 527-728) (ABIN3043259)
抗原
See all ITGB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 527-728
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原理
- Anti-Integrin beta 1/ITGB1 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human ITGB1 shares 91%,88% amino acid (aa) sequences identity with mouse,rat ITGB1,respectively.
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产品特性
- Anti-Integrin beta 1/ITGB1 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ITGB1 recombinant protein (Position: N527-D728). Human ITGB1 shares 91% and 88% amino acid (aa) sequences identity with mouse and rat ITGB1, respectively.
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亚型
- IgG
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Isolation and morphological characterization of ovine amniotic fluid mesenchymal stem cells." in: Experimental animals, Vol. 65, Issue 2, pp. 125-34, (2017) (PubMed).
: "Effects of human umbilical cord mesenchymal stem cell transplantation combined with minimally invasive hematoma aspiration on intracerebral hemorrhage in rats." in: American journal of translational research, Vol. 7, Issue 11, pp. 2176-86, (2016) (PubMed).
: "Suppression of A549 cell proliferation and metastasis by calycosin via inhibition of the PKC-α/ERK1/2 pathway: An in vitro investigation." in: Molecular medicine reports, Vol. 13, Issue 4, pp. 3709-10, (2016) (PubMed).
: "Abnormalities in the basement membrane structure promote basal keratinocytes in the epidermis of hypertrophic scars to adopt a proliferative phenotype." in: International journal of molecular medicine, Vol. 37, Issue 5, pp. 1263-73, (2016) (PubMed).
: "Effect of mixed transplantation of autologous and allogeneic microskin grafts on wound healing in a rat model of acute skin defect." in: PLoS ONE, Vol. 9, Issue 1, pp. e85672, (2014) (PubMed).
: "Nanog and ?-catenin: a new convergence point in EpSC proliferation and differentiation." in: International journal of molecular medicine, Vol. 29, Issue 4, pp. 587-92, (2012) (PubMed).
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- ITGB1 (Integrin beta 1 (ITGB1))
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别名
- ITGB1
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背景
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Background: Integrin beta-1, also known as CD29, is a protein that in humans is encoded by the ITGB1 gene. CD29 is an integrin unit associated with very late antigen receptors. It is known to conjoin with alpha-3 subunit to create alpha3beta1 complex that reacts to such molecules as netrin-1 and reelin. This gene contains a beta subunit that appears to be analogous to band-3 of integrin. It is mapped to 10p11.22. It is found that FER mediates crosstalk between CDH2 and CD29. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. The protein encoded by this gene is a beta subunit.
Gene Full Name: integrin subunit beta 1
Sequence Similarities: Belongs to the integrin beta chain family.
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分子量
- 120-130 kDa
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基因ID
- 3688
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UniProt
- P05556
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途径
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
抗原
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