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IL12B 抗体 (N-Term)

Name: IL12B 抗体 (N-Term)
SKU: ABIN3043199
Availability: OutOfStock

This anti-IL12B antibody is a 兔多克隆 antibody detecting IL12B in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.

Western Blotting (WB) image for anti-Interleukin 12 beta (IL12B) (AA 23-40), (N-Term) antibody (ABIN3043199) (IL12B 抗体 (N-Term))

1 image

(1 reference)

产品编号 ABIN3043199

发货至: 中国

Quick Overview for IL12B 抗体 (N-Term) (ABIN3043199)

抗原

See all IL12B 抗体

IL12B (Interleukin 12 beta (IL12B))

适用

人

宿主

兔

克隆类型

多克隆

标记

This IL12B antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product IL12B Primary Antibody

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AA 23-40, N-Term

原理

Anti-IL12 p40/IL12B Antibody Picoband®

序列

IWELKKDVYV VELDWYPD

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-IL12 p40/IL12B Antibody (ABIN3043199). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human IL-12(p40).

亚型

IgG
anti-Interleukin 12 beta (IL12B) (AA 201-300) antibody
IL12B 适用: 人, 小鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 12 beta (IL12B) (AA 30-320) antibody
IL12B 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C12 unconjugated

anti-Interleukin 12 beta (IL12B) (AA 23-327) antibody
IL12B 适用: 绵羊 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 12 beta (IL12B) (AA 23-328) antibody
IL12B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 12 beta (IL12B) (Internal Region) antibody
Verified IL12B 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Interleukin 12 beta (IL12B) (Internal Region) antibody
Verified IL12B 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Interleukin 12 beta (IL12B) (AA 229-328) antibody
IL12B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H6 unconjugated

anti-Interleukin 12 beta (IL12B) (AA 35-302) antibody
IL12B 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 12 beta (IL12B) antibody
IL12B 适用: 人, Pig ELISA, IHC (fro) 宿主: 小鼠 Monoclonal I-1A4 unconjugated

anti-Interleukin 12 beta (IL12B) (C-Term) antibody
IL12B 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human
1. Gunsten, S., Mikols, C. L., Grayson, M. H., Schwendener, R. A., Agapov, E., Tidwell, R. M., Cannon, C. L., Brody, S. L., Walter, M. J.IL-12 p80-dependent macrophage recruitment primes the host for increased survival following a lethal respiratory viral infection.Immunology 126: 500-513, 2008. 2. Oppmann, B., Lesley, R., Blom, B., Timans, J. C., Xu, Y., Hunte, B., Vega, F., Yu, N., Wang, J., Singh, K., Zonin, F., Vaisberg, E., and 13 others.Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.Immunity 13: 715-725, 2000. 3. Sieburth, D., Jabs, E. W., Warrington, J. A., Li, X., Lasota, J., LaForgia, S., Kelleher, K., Huebner, K., Wasmuth, J. J., Wolf, S. F.Assignment of genes encoding a unique cytokine (IL12) composed of two unrelated subunits to chromosomes 3 and 5.Genomics 14: 59-62, 1992.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Dong, Xia, Chen, Chen, Zhang: "Anti-arthritis activity of cationic materials." in: Journal of cellular and molecular medicine, Vol. 14, Issue 7, pp. 2015-24, (2011) (PubMed).
抗原

IL12B (Interleukin 12 beta (IL12B))

别名

IL12B

背景

Synonyms: Interleukin-12 subunit beta,IL-12B,Cytotoxic lymphocyte maturation factor 40 kDa subunit,CLMF p40,IL-12 subunit p40,NK cell stimulatory factor chain 2,NKSF2,IL12B,NKSF2,
Background: IL-12, Interleukin 12, heterodimerizes with the IL12 p35 subunit to form IL12 and with the IL23 p19 subunit to form IL23. IL12b p 40 exists as a monomer and as a homodimer. This gene encodes a subunit of Interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The IL-12b gene contains 8 exons, the first and last of which are noncoding. By PCR analysis of DNA from rodent/human cell hybrids containing intact chromosomes or translocation chromosomes, the IL-12b gene is mapped to 5q31-q33.This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.
Sequence Similarities: Belongs to the type I cytokine receptor family. Type 3 subfamily.

分子量

20 kDa

UniProt

P29460

途径

JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation