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IL12B 抗体 (N-Term)

There is 1 publication for this product available. The 兔 多克隆 anti-IL12B antibody is suitable to detect IL12B in samples from 人. It has been validated for WB.
产品编号 ABIN3043199
发货至: 中国
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Quick Overview for IL12B 抗体 (N-Term) (ABIN3043199)

抗原

See all IL12B 抗体
IL12B (Interleukin 12 beta (IL12B))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL12B antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    AA 23-40, N-Term

    原理

    Anti-IL12 p40/IL12B Antibody

    序列

    IWELKKDVYV VELDWYPD

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-IL12 p40/IL12B Antibody (ABIN3043199). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human IL-12(p40).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Dong, Xia, Chen, Chen, Zhang: "Anti-arthritis activity of cationic materials." in: Journal of cellular and molecular medicine, Vol. 14, Issue 7, pp. 2015-24, (2011) (PubMed).

  • 抗原

    IL12B (Interleukin 12 beta (IL12B))

    别名

    IL12B

    背景

    Synonyms: Interleukin-12 subunit beta,IL-12B,Cytotoxic lymphocyte maturation factor 40 kDa subunit,CLMF p40,IL-12 subunit p40,NK cell stimulatory factor chain 2,NKSF2,IL12B,NKSF2,

    Background: IL-12, Interleukin 12, heterodimerizes with the IL12 p35 subunit to form IL12 and with the IL23 p19 subunit to form IL23. IL12b p 40 exists as a monomer and as a homodimer. This gene encodes a subunit of Interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The IL-12b gene contains 8 exons, the first and last of which are noncoding. By PCR analysis of DNA from rodent/human cell hybrids containing intact chromosomes or translocation chromosomes, the IL-12b gene is mapped to 5q31-q33.This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.

    Sequence Similarities: Belongs to the type I cytokine receptor family. Type 3 subfamily.

    分子量

    20 kDa

    UniProt

    P29460

    途径

    JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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