CD147 抗体 (Middle Region)
(3 references)Quick Overview for CD147 抗体 (Middle Region) (ABIN3043170)
抗原
See all CD147 (BSG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 186-203, Middle Region
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原理
- Anti-CD147/BSG Antibody Picoband®
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序列
- QKTEFKVDSD DQWGEYSC
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-/BSG Antibody (ABIN3043170). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human CD147.
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亚型
- IgG
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anti-Basigin (Ok Blood Group) (BSG) (AA 79-280) antibody
BSG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Basigin (Ok Blood Group) (BSG) (AA 87-323) antibodyBSG 适用: 小鼠 WB, FACS, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Basigin (Ok Blood Group) (BSG) (AA 59-321) antibodyBSG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Basigin (Ok Blood Group) (BSG) (AA 30-200) antibodyBSG 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Basigin (Ok Blood Group) (BSG) (AA 138-323) antibodyBSG 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 7H4D4 unconjugated
anti-Basigin (Ok Blood Group) (BSG) (AA 138-323) antibodyBSG 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 2D8C11 unconjugated
anti-Basigin (Ok Blood Group) (BSG) (AA 138-323) antibodyBSG 适用: 人 WB, FACS, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Basigin (Ok Blood Group) (BSG) (AA 138-323) antibodyBSG 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 3E10C1 unconjugated
anti-Basigin (Ok Blood Group) (BSG) antibodyBSG 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal BSG-963 unconjugated
anti-Basigin (Ok Blood Group) (BSG) (AA 1-269) antibodyBSG 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human1. Guo, H., Majmudar, G., Jensen, T. C., Biswas, C., Toole, B. P., Gordon, M. K.Characterization of the gene for human EMMPRIN, a tumor cell surface inducer of matrix metalloproteinases.Gene 220: 99-108, 1998. 2. Zhou, S., Zhou, H., Walian, P. J., Jap, B. K.CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "iTRAQ-coupled 2D LC/MS-MS analysis of CXCR7-transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of ..." in: Oncology letters, Vol. 14, Issue 3, pp. 3734-3740, (2017) (PubMed).
: "Overexpression of CD147 is associated with poor prognosis, tumor cell migration and ERK signaling pathway activation in hepatocellular carcinoma." in: Experimental and therapeutic medicine, Vol. 14, Issue 3, pp. 2637-2642, (2017) (PubMed).
: "Expression and clinical significance of extracellular matrix metalloproteinase inducer, EMMPRIN/CD147, in human osteosarcoma." in: Oncology letters, Vol. 5, Issue 1, pp. 201-207, (2012) (PubMed).
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: "iTRAQ-coupled 2D LC/MS-MS analysis of CXCR7-transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of ..." in: Oncology letters, Vol. 14, Issue 3, pp. 3734-3740, (2017) (PubMed).
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- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
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别名
- BSG
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背景
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Synonyms: Basigin,5F7,Collagenase stimulatory factor,Extracellular matrix metalloproteinase inducer,EMMPRIN,Leukocyte activation antigen M6,OK blood group antigen,Tumor cell-derived collagenase stimulatory factor,TCSF,CD147,BSG,UNQ6505/PRO21383,
Tissue Specificity: Present only in vascular endothelium in non- neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas.
Background: Emmprin, extracellular matrix metalloproteinase inducer, also known as Emmprin (BSG) or cluster of differentiation 147 (CD147) is a protein that in humans is encoded by the Emmprin gene. the BSG gene contains 8 exons and spans 10.8 kb. The human BSG gene is mapped to 19p13.3. This protein is a determinant for the Ok blood group system. Emmprin has been shown to be an essential receptor on red blood cells for the malaria parasite. Emmprin is a member of the immunoglobulin superfamily, with a structure related to the putative primordial form of the family. As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development, Emmprin is though also to play a role in intercellular recognition. Emmprin also regulates several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. Emmprin is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins. It is expressed by many cell types, including epithelial cells, endothelial cells and leukocytes.
Sequence Similarities: Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
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分子量
- 35-60 kDa
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UniProt
- P35613
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途径
- S100 Proteins
抗原
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