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STRA8 抗体 (C-Term)

This anti-STRA8 antibody is a 兔 多克隆 antibody detecting STRA8 in WB. Suitable for 大鼠.
产品编号 ABIN3043169
发货至: 中国

Quick Overview for STRA8 抗体 (C-Term) (ABIN3043169)

抗原

See all STRA8 抗体
STRA8 (Stimulated By Retinoic Acid 8 (STRA8))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This STRA8 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 341-355, C-Term

    原理

    Anti-Stra8 Antibody Picoband®

    序列

    DDDVMLLKCL ETFDD

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Stra8 Antibody (ABIN3043169). Tested in WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of rat Stra8, different from the related mouse sequence by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Rat
    1. Anderson, E. L., Baltus, A. E., Roepers-Gajadien, H. L., Hassold, T. J., de Rooij, D. G., van Pelt, A. M. M., Page, D. C.Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice.Proc. Nat. Acad. Sci. 105: 14976-14980, 2008. 2. Miyamoto, T., Sengoku, K., Takuma, N., Hasuike, S., Hayashi, H., Yamauchi, T., Yamashita, T., Ishikawa, M.Isolation and expression analysis of the testis-specific gene, STRA8, stimulated by retinoic acid gene 8.J. Assisted Reprod. Genet. 19: 531-535, 2002.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    STRA8 (Stimulated By Retinoic Acid 8 (STRA8))

    别名

    STRA8

    背景

    Synonyms: Protein Stra8 ,Stra8 ,

    Tissue Specificity: Present only in vascular endothelium in non- neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas.

    Background: Stra8, stimulated by retinoic acid 8, is expressed in embryonic ovaries just before meiotic initiation, whereas in testis it is expressed after birth. The STRA8 gene contains 9 exons. And this gene is mapped to chromosome 7q31. Retinoic acid (RA) signaling was required for Stra8 expression, and therefore initiation of meiosis, in embryonic mouse ovaries. RA was sufficient to induce Stra8 expression in embryonic testis. Cyp26-mediated RA metabolism was responsible for delaying Stra8 expression in embryonic testis. Since RA signaling regulated Stra8 expression in both embryonic ovaries and adult testis, it was said this portion of the meiotic initiation pathway may be identical in both sexes.

    Sequence Similarities: Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

    分子量

    37 kDa
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