CHRNA1 抗体 (N-Term)
Quick Overview for CHRNA1 抗体 (N-Term) (ABIN3043100)
抗原
See all CHRNA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-36, N-Term
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原理
- Anti-Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 Antibody Picoband®
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序列
- EHETRLVAKL FKDYS
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 Antibody (ABIN3043100). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Nicotinic Acetylcholine Receptor alpha 1, identical to the related rat sequence, different from the related mouse sequence by one amino acid.
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亚型
- IgG
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anti-Acetylcholine Receptor Subunit alpha (CHRNA1) (AA 25-240) antibody
CHRNA1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholine Receptor Subunit alpha (CHRNA1) (AA 21-255) antibodyCHRNA1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholine Receptor Subunit alpha (CHRNA1) (N-Term) antibodyCHRNA1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholine Receptor Subunit alpha (CHRNA1) (C-Term) antibodyCHRNA1 适用: 人, 小鼠, 大鼠, 犬, Cow, 小鸡 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholine Receptor Subunit alpha (CHRNA1) (C-Term) antibodyCHRNA1 适用: 人, 小鼠, 犬, 豚鼠, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholine Receptor Subunit alpha (CHRNA1) (AA 21-255) antibodyCHRNA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholine Receptor Subunit alpha (CHRNA1) (C-Term) antibodyCHRNA1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholine Receptor Subunit alpha (CHRNA1) (AA 25-234) antibodyCHRNA1 适用: Torpedo californica ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholine Receptor Subunit alpha (CHRNA1) (AA 21-230) antibodyCHRNA1 适用: 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholine Receptor Subunit alpha (CHRNA1) (AA 146-231) antibodyCHRNA1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2G5 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Giraud, M., Taubert, R., Vandiedonck, C., Ke, X., Levi-Strauss, M., Pagani, F., Baralle, F. E., Eymard, B., Tranchant, C., Gajdos, P., Vincent, A., Willcox, N., Beeson, D., Kyewski, B., Garchon, H.-J. : An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus. Nature 448: 934-937, 2007. 2. Noda, M., Furutani, Y., Takahashi, H., Toyosato, M., Tanabe, T., Shimizu, S., Kikyotani, S., Kayano, T., Hirose, T., Inayama, S., Numa, S. : Cloning and sequence analysis of calf cDNA and human genomic DNA encoding alpha-subunit precursor of muscle acetylcholine receptor. Nature 305: 818-823, 1983. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))
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别名
- CHRNA1
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背景
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Synonyms: Acetylcholine receptor subunit alpha,CHRNA1,ACHRA, CHNRA,
Tissue Specificity: Isoform 1 is only expressed in skeletal muscle. Isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus.
Background: CHRNA, also termed ACHRA, is mapped on 2q24-q32.This gene encodes the alpha subunit of the muscle acetylcholine receptor, which is the main target of pathogenic autoantibodies in autoimmune myasthenia gravis. The protein-coding sequence of the human alpha subu gene is divided into 9 exons that correspond to different structural and functional domains of the precursor molecule.
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分子量
- 69 kDa
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UniProt
- P02708
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途径
- Skeletal Muscle Fiber Development
抗原
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