Aryl Hydrocarbon Receptor 抗体 (C-Term)
Quick Overview for Aryl Hydrocarbon Receptor 抗体 (C-Term) (ABIN3043054)
抗原
See all Aryl Hydrocarbon Receptor (AHR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 832-848, C-Term
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原理
- Anti-Aryl hydrocarbon Receptor/AHR Antibody Picoband®
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序列
- HPSEARPFPD LTSSGFL
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Aryl hydrocarbon Receptor/AHR Antibody (ABIN3043054). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human AHR.
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亚型
- IgG
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anti-Aryl Hydrocarbon Receptor (AHR) (AA 721-820) antibody
AHR 适用: 人 WB, ELISA, IF, IP, RNAi 宿主: 小鼠 Monoclonal 3B12 unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) (AA 619-848) antibodyAHR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) (AA 555-582) antibodyAHR 适用: 人, 小鼠 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) (pSer36) antibodyAHR 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) (N-Term) antibodyAHR 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) (AA 721-820) antibodyAHR 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G7 unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) (Internal Region) antibodyVerified AHR 适用: 人 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) (AA 721-820) antibodyAHR 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5E6A9 unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) (N-Term) antibodyAHR 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) (AA 126-353) antibodyAHR 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Andersson, P., McGuire, J., Rubio, C., Gradin, K., Whitelaw, M. L., Pettersson, S., Hanberg, A., Poellinger, L. A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors. Proc. Nat. Acad. Sci. 99: 9990-9995, 2002. 2. Ema, M., Matsushita, N., Sogawa, K., Ariyama, T., Inazawa, J., Nemoto, T., Ota, M., Oshimura, M., Fujii-Kuriyama, Y. Human arylhydrocarbon receptor: functional expression and chromosomal assignment to 7p21. J. Biochem. 116: 845-851, 1994. 3. Le Beau, M. M., Carver, L. A., Espinosa, R., III, Schmidt, J. V., Bradfield, C. A. Chromosomal localization of the human AHR locus encoding the structural gene for the Ah receptor to 7p21-p15. Cytogenet. Cell Genet. 66: 172-176, 1994. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Aryl Hydrocarbon Receptor (AHR)
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别名
- AHR
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背景
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Synonyms: Aryl hydrocarbon receptor;Ah receptor;AhR;Class E basic helix-loop-helix protein 76;bHLHe76;AHR;BHLHE76;
Tissue Specificity: Expressed in all tissues tested including blood, brain, heart, kidney, liver, lung, pancreas and skeletal muscle. .
Background: AHR (aryl hydrocarbon receptor), also called bHLHe76, is a member of the family of basic helix-loop-helix transcription factors. AhR is a cytosolic transcription factor that is normally inactive, bound to several co-chaperones. The AHR gene is mapped on 7p21.1. Estrogenic actions of AHR agonists were detected in wildtype ovariectomized mouse uteri, but were absent in Ahr -/- or Er-alpha -/- ovariectomized mice. Complex assembly and ubiquitin ligase activity of CUL4B (AHR) in vitro and in vivo are dependent on the AHR ligand. In the CUL4B (AHR) complex, ligand-activated AHR acts as a substrate-specific adaptor component that targets sex steroid receptors for degradation. Cd4-positive cells from mice lacking Ahr developed Th17 responses but failed to produce Il22 and did not show enhanced Th17 development. Activation of Ahr during induction of EAE accelerated disease onset and increased pathology in wildtype mice, but not in Ahr -/- mice. The TDO-AHR pathway is active in human brain tumors and is associated with malignant progression and poor survival. Ahr activity within ROR-gamma-t-positive ILC could be induced by dietary ligands such as those contained in vegetables of the family Brassicaceae.
Sequence Similarities: Contains 1 bHLH (basic helix-loop-helix) domain.
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分子量
- 100-110 kDa
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UniProt
- P35869
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途径
- Regulation of Cell Size
抗原
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