(1 reference)-
- 抗原 See all E2F2 抗体
- E2F2 (E2F Transcription Factor 2 (E2F2))
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抗原表位
- AA 422-427, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This E2F2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Anti-Transcription factor E2F2 E2F2 Antibody Picoband®
- 序列
- ISDLFDSYDL GDLLIN
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-Transcription factor E2F2 E2F2 Antibody (ABIN3043044). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human E2F2, identical to the related mouse sequence.
- 亚型
- IgG
- Top Product
- Discover our top product E2F2 Primary Antibody
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anti-E2F Transcription Factor 2 (E2F2) (AA 1-83) antibody
E2F2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) (AA 1-437) antibodyE2F2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) (Internal Region) antibodyE2F2 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) (Middle Region) antibodyE2F2 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) (AA 1-110) antibodyE2F2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) (Internal Region) antibodyE2F2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) (AA 1-83) antibodyE2F2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) antibodyE2F2 适用: 人 DB 宿主: 小鼠 Monoclonal 2302C4a unconjugated
anti-E2F Transcription Factor 2 (E2F2) (AA 258-286) antibodyE2F2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB27633 unconjugated
anti-E2F Transcription Factor 2 (E2F2) (Middle Region) antibodyE2F2 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Chen, D., Pacal, M., Wenzel, P., Knoepfler, P. S., Leone, G., Bremner, R. Division and apoptosis of E2f-deficient retinal progenitors. Nature 462: 925-929, 2009. 2. Funke-Kaiser, H., Reichenberger, F., Kopke, K., Herrmann, S.-M., Pfeifer, J., Orzechowski, H.-D., Zidek, W., Paul, M., Brand, E. Differential binding of transcription factor E2F-2 to the endothelin-converting enzyme-1b promoter affects blood pressure regulation. Hum. Molec. Genet. 12: 423-433, 2003. 3. Lees, J. A., Saito, M., Vidal, M., Valentine, M., Look, T., Harlow, E., Dyson, N., Helin, K. The retinoblastoma protein binds to a family of E2F transcription factors. Molec. Cell. Biol. 13: 7813-7825, 1993. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. - 有效期
- 12 months
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: "GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 and AKT Signaling Pathways." in: International journal of molecular sciences, Vol. 16, Issue 9, pp. 21897-910, (2016) (PubMed).
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: "GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 and AKT Signaling Pathways." in: International journal of molecular sciences, Vol. 16, Issue 9, pp. 21897-910, (2016) (PubMed).
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- 抗原
- E2F2 (E2F Transcription Factor 2 (E2F2))
- 别名
- E2F2 (E2F2 产品)
- 背景
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Synonyms: Transcription factor E2F2;E2F-2;E2F2;
Tissue Specificity: Highest level of expression is found in placenta, low levels are found in lung. Found as well in many immortalized cell lines derived from tumor samples.
Background: E2F2 (E2F transcription factor 2) also called E2F-2, is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F2 gene is mapped to 1p36 by fluorescence in situ hybridization. Electrophoretic mobility shift assays revealed the specific binding of E2F2 to ECE1b promoter sequences containing either allele of the C-338A polymorphism, with the -338A allele being associated with an increased affinity to E2F2 compared with -338C. The ability of Myc to induce S phase was impaired in the absence of either E2f2 or E2f3 but not E2f1 or E2f4. In contrast, the ability of Myc to induce apoptosis was markedly reduced in cells deleted for E2f1 but not E2f2 or E2f3.
Sequence Similarities: Belongs to the E2F/DP family.
- 分子量
- 48 kDa
- UniProt
- Q14209
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication
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