HYAL2 抗体 (C-Term)
Quick Overview for HYAL2 抗体 (C-Term) (ABIN3043041)
抗原
See all HYAL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 142-157, C-Term
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原理
- Anti-Hyaluronidase-2 HYAL2 Antibody Picoband®
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序列
- VRNWQDKDVY RRLSRQ
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Hyaluronidase-2 HYAL2 Antibody (ABIN3043041). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human HYAL2, different from the related mouse and rat sequences by three amino acids.
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亚型
- IgG
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anti-Hyaluronidase-2 (HYAL2) (AA 111-210) antibody
HYAL2 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronidase-2 (HYAL2) (AA 23-447) antibodyHYAL2 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronidase-2 (HYAL2) (AA 367-473) antibodyHYAL2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronidase-2 (HYAL2) antibodyHYAL2 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronidase-2 (HYAL2) (AA 340-439) antibodyHYAL2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Hyaluronidase-2 (HYAL2) (AA 385-412), (C-Term) antibodyHYAL2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24065 unconjugated
anti-Hyaluronidase-2 (HYAL2) (AA 388-416), (C-Term) antibodyHYAL2 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronidase-2 (HYAL2) (AA 1-473) antibodyHYAL2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hyaluronidase-2 (HYAL2) (C-Term) antibodyHYAL2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronidase-2 (HYAL2) (AA 128-157) antibodyHYAL2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB31073 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Lepperdinger, G., Strobl, B., Kreil, G. HYAL2, a human gene expressed in many cells, encodes a lysosomal hyaluronidase with a novel type of specificity. J. Biol. Chem. 273: 22466-22470, 1998. 2. Rai, S. K., Duh, F.-M., Vigdorovich, V., Danilkovitch-Miagkova, A., Lerman, M. I., Miller, A. D. Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation. Proc. Nat. Acad. Sci. 98: 4443-4448, 2001. 3. Strobl, B., Wechselberger, C., Beier, D. R., Lepperdinger, G. Structural organization and chromosomal localization of Hyal2, a gene encoding a lysosomal hyaluronidase. Genomics 53: 214-219, 1998. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- HYAL2 (Hyaluronidase-2 (HYAL2))
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别名
- HYAL2
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背景
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Synonyms: Hyaluronidase-2;Hyal-2;3.2.1.35;Hyaluronoglucosaminidase-2;Lung carcinoma protein 2;LuCa-2;HYAL2;LUCA2;
Tissue Specificity: Widely expressed. No expression detected in adult brain. .
Background: HYAL2 (hyaluronoglucosaminidase 2) also known as hyaluronidase 2, LuCa-2, is an enzyme that in humans is encoded by the HYAL2 gene. HYAL2 cDNAs encode a preprotein with an N-terminal signal peptide. Northern blot analysis indicated that HYAL2 was expressed in all human tissues tested except adult brain, and Western blot analysis detected Hyal2protein in all mouse tissues examined except adult brain. The HYAL2 gene is mapped on 3p21.31. HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored protein on the cell surface and serves as a receptor for entry into the cell of the jaagsiekte sheep retrovirus (JSRV). The findings of Rai et al. (2001) that HYAL2 is a GPI-anchored protein on the cell surface showed that GFP would likely be cleaved from HYAL2 during GPI addition, leaving HYAL2 on the cell surface and resulting in GFP transit to the lysosome for degradation.
Sequence Similarities: Belongs to the glycosyl hydrolase 56 family.
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分子量
- 54 kDa
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UniProt
- Q12891
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途径
- Transition Metal Ion Homeostasis, Glycosaminoglycan Metabolic Process
抗原
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