High Mobility Group B Protein 4 (HMGB4) (N-Term) 抗体
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Quick Overview for High Mobility Group B Protein 4 (HMGB4) (N-Term) 抗体 (ABIN3043021)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-High mobility group protein B4 HMGB4 Antibody
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序列
- RNKFKEQQPN TYVGFKEF
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse,rat sequences by one amino acid.
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产品特性
- Anti-High mobility group protein B4 HMGB4 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human HMGB4, different from the related mouse and rat sequences by one amino acid.
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亚型
- IgG
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "HMGB4 is expressed by neuronal cells and affects the expression of genes involved in neural differentiation." in: Scientific reports, Vol. 6, pp. 32960, (2018) (PubMed).
: "HMGB1, TGF-β and NF-κB are associated with chronic allograft nephropathy." in: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 6138-6146, (2017) (PubMed).
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- High Mobility Group B Protein 4 (HMGB4)
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别名
- HMGB4
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背景
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Background: HMGB4 is HMG2 like, isoform 2, high-mobility group box 4. This gene can be found on Chromosome 1. HMGB4 contains two HMG-box regions, which is found in a variety of eukaryotic chromosomal proteins and transcription. HMGB proteins are phosphorylated to various extents reveals that the existence of differentially modified forms increases the number of distinct HMGB protein variants in plant chromatin that may be adapted to certain functions.
Gene Full Name: high mobility group box 4
Sequence Similarities: Belongs to the HMGB family.
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分子量
- 23 kDa
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基因ID
- 127540
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UniProt
- Q8WW32
抗原
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